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Scholar Results 1 - 10 of about 101 related to Steffes: β-Cell function and the development of diabetes-related complications in the Diabetes.... (0.11 sec) 

β-Cell function and the development of diabetes-related complications in the Diabetes …

- diabetesjournals.org
MW Steffes, S Sibley, M Jackson, W Thomas - Diabetes Care, 2003 - Am Diabetes Assoc
In patients with type 1 diabetes, measurement of connecting peptide (C-peptide),
cosecreted with insulin from the islets of Langerhans, permits estimation of
remaining β-cell secretion of insulin. In this retrospective analysis to ...
Cited by 112 - Related articles - BL Direct - All 5 versions

Michael W. Steffes, MD, PHD


S Sibley - Diabetes Care, 2003 - Am Diabetes Assoc
In patients with type 1 diabetes, measurement of connecting peptide (C-peptide),
cosecreted with insulin from the islets of Langerhans, permits estimation of
remaining -cell secretion of insulin. In this retrospective analysis to ...
Related articles

Insulin secretion in type 1 diabetes


C Steele, WA Hagopian, S Gitelman, U … - Diabetes, 2004 - Am Diabetes Assoc
Type 1 diabetes, a chronic autoimmune disease, causes destruction of
insulin-producing β-cells over a period of years. Although many markers of the
autoimmune process have been described, none can convincingly predict the ...
Cited by 54 - Related articles - BL Direct - All 4 versions

C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve …


JP Palmer, GA Fleming, CJ Greenbaum, KC … - Diabetes, 2004 - ncbi.nlm.nih.gov
The underlying cause of type 1 diabetes, loss of beta-cell function, has become
the therapeutic target for a number of interventions in patients with type 1
diabetes. Even though insulin therapies continue to improve, it remains ...
Cited by 88 - Related articles - BL Direct

C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve β …


JP Palmer, GA Fleming, CJ Greenbaum, KC … - Diabetes, 2004 - Am Diabetes Assoc
The underlying cause of type 1 diabetes, loss of β-cell function, has become
the therapeutic target for a number of interventions in patients with type 1
diabetes. Even though insulin therapies continue to improve, it remains ...
Cited by 27 - Related articles - All 2 versions

Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention Trial–Type 1

- Free from Publisher
JM Sosenko, JP Palmer, CJ Greenbaum, J … - Diabetes Care, 2006 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Fifty-four DPT-1 participants (22 in the
parenteral trial and 32 in the oral trial) were studied. All had oral glucose
tolerance tests (OGTTs) at 6-month intervals from approximately 30 to 6 ...
Cited by 39 - Related articles - BL Direct - All 5 versions

Use of an islet cell antibody assay to identify type 1 diabetic patients with rapid decrease in …

- diabetesjournals.org [PDF] 
K Decochez, B Keymeulen, G Somers, H Dorchy, … - Diabetes Care, 2000 - Am Diabetes Assoc
Type 1 diabetes is caused by an immune-mediated destruction of pancreatic
insulin-producing -cells (1). The histopathological hallmarks of the disease
comprise a markedly reduced -cell mass and a focal infiltration of the ...
Cited by 31 - Related articles - BL Direct - All 6 versions

Residual insulin production, glycaemic control and prevalence of microvascular lesions and …


S Sjöberg, R Gunnarsson, M Gjötterberg, AK … - Diabetologia, 1987 - Springer
Summary. The aim of the present study was to evaluate the role of residual
insulin production in long-term Type I (insu- lin-dependent) diabetes mellitus.
Ninety-seven patients with a disease duration of 9-16 years and onset ...
Cited by 46 - Related articles - All 3 versions

Parameters associated with residual insulin secretion during the first year of disease in …


R Bonfanti, E Bazzigaluppi, G Calori, MC Riva, … - Diabetic Medicine, 1998 - interscience.wiley.com
Factors associated with residual insulin secretion and spontaneous remission in
Type 1 diabetic patients are important in the evaluation of treatment aimed at
modifying the natural history of Type 1 DM. We investigated the effect of ...
Cited by 46 - Related articles - BL Direct - All 4 versions

Prognostic Factors for the Course of {beta} Cell Function in Autoimmune Diabetes

- endojournals.org
C Torn, M Landin-Olsson, A Lernmark, JP … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc
This study presents a 2-yr follow-up of 281 patients, aged 15–34 yr, diagnosed
with diabetes between 1992 and 1993. At diagnosis, 224 (80%) patients were
positive for at least one of the following autoantibodies: islet cell ...
Cited by 54 - Related articles - BL Direct - All 4 versions


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