SK Jain, K Kannan, G Lim, J Matthews-Greer, R … - Diabetes Care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Fasting blood was obtained from type 1 diabetic patients
and healthy siblings. To examine the effect of ketosis, U937 monocytes were cultured with ketone
bodies (acetoacetate [AA], β-hydroxybutyrate [BHB]) in the presence or absence of high ... Cited by 31 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org MA Abdelmegeed, SK Kim, KJ Woodcroft, RF … - Journal of Pharmacology …, 2004 - ASPET Diabetes is characterized by elevated levels of ketone bodies acetoacetate (AA) and 3-hydroxybutyrate
(3HB). High levels of ketone bodies have been implicated in generation of cellular oxidative
stress. Ketone body activation of cellular signaling pathways associated with oxidative ... Cited by 15 - Related articles - BL Direct - All 3 versions
CG Schalkwijk, PM Wee, CDA … - ANNALS-NEW YORK …, 2005 - interscience.wiley.com Abstract: Patients with renal impairment have an increased risk for cardiovascular disease, which
may be the result of advanced glycation end products (AGEs). The aim of this study was to investigate
the levels of AGE peptides in relation to kidney function and to study the relationship of ... Cited by 12 - Related articles - BL Direct - All 5 versions
B Kulseng, G Skjak-Braek, I Folling, T … - … Journal of Immunology, 1996 - interscience.wiley.com Microencapsulated pancreatic Langerhan's islets in calcium alginate gels have been used as
an implantable bio-artificial pancreas in the treatment of diabetes mellitus, but with limited success
due to overgrowth of the capsule with fibroblasts and phagocytes. The authors earlier ... Cited by 22 - Related articles - BL Direct - All 5 versions
[CITATION] Effect of hyperketonemia on lipid peroxidation levels of plasma in diabetic patients
WH Hoffman, C Cheng, GG Passmore, JE Carroll, D … - Neuroscience letters, 2002 - Elsevier It has been hypothesized that ketone bodies cause activation of brain endothelial cells and that
this is a factor in the intracerebral crises of diabetic ketoacidosis (DKA). In this study we used
cultured human brain microvascular endothelial cells (HBMEC) to investigate the effect of ... Cited by 15 - Related articles - All 6 versions
SK Jain, K Kannan, G Lim - Free Radical Biology and Medicine, 1998 - Elsevier Elevated level of cellular lipid peroxidation can increase the incidence of vascular disease. The
mechanism by which ketosis causes accelerated cellular damage and vascular disease in diabetes
is not known. This study was undertaken to test the hypothesis that elevated levels of ... Cited by 50 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] SK Jain, R McVie - Diabetes, 1999 - Am Diabetes Assoc Recent studies have suggested that elevated cellular lipid peroxidation may play a role in the
development of cellular dysfunction and other complications of diabetes. People with type 1 diabetes
frequently encounter elevated levels of the ketone bodies ace- toacetate (AA), ß- ... Cited by 51 - Related articles - BL Direct - All 5 versions
