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Scholar Results 1 - 10 of about 101 related to Torgerson: Xenical in the prevention of diabetes in obese subjects (XENDOS) study. (0.13 sec) 

Xenical in the prevention of diabetes in obese subjects (XENDOS) study


JS Torgerson, J Hauptman, MN Boldrin, L Sjöström - Diabetes Care, 2004 - Am Diabetes Assoc
RESULTS—Of orlistat-treated patients, 52% completed treatment compared with 34% of placebo
recipients (P < 0.0001). After 4 years' treatment, the cumulative incidence of diabetes was
9.0% with placebo and 6.2% with orlistat, corresponding to a risk reduction of 37.3% (P = ...
Cited by 737 - Related articles - BL Direct - All 10 versions

Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised …


JL Chiasson, RG Josse, R Gomis, M Hanefeld, A … - The Lancet, 2002 - Elsevier
We randomly allocated 714 patients with impaired glucose tolerance to acarbose and 715 to
placebo. We excluded 61 (4%) patients because they did not have impaired glucose tolerance
or had no postrandomisation data. 211 (31%) of 682 patients in the acarbose group and ...
Cited by 1218 - Related articles - All 14 versions

Effect of sibutramine on weight maintenance after weight loss: a randomised trial

- lindaxa.cz [PDF] 
WPT James, A Astrup, N Finer, J Hilsted, P Kopelman, … - The Lancet, 2000 - Elsevier
Eight European centres recruited 605 obese patients (body-mass index 30-45 kg/m 2 ) for a
6-month period of weight loss with sibutramine (10 mg/day) and an individualised 600 kcal/day
deficit programme based on measured resting metabolic rates. 467 (77%) patients with ...
Cited by 656 - Related articles - BL Direct - All 10 versions

Preservation of pancreatic β-cell function and prevention of type 2 diabetes by …

- diabetesjournals.org
TA Buchanan, AH Xiang, RK Peters, SL Kjos, A … - Diabetes, 2002 - Am Diabetes Assoc
Type 2 diabetes frequently results from progressive failure of pancreatic β-cell function in the
presence of chronic insulin resistance. We tested whether chronic amelioration of insulin resistance
would preserve pancreatic β-cell function and delay or prevent the onset of type 2 ...
Cited by 926 - Related articles - BL Direct - All 6 versions

Clinical efficacy of orlistat therapy in overweight and obese patients with insulin- …


DE Kelley, GA Bray, FX Pi-Sunyer, S Klein, J Hill, J … - Diabetes Care, 2002 - Am Diabetes Assoc
OBJECTIVE—Weight loss improves glycemic control, lipid profiles, and blood pressure in patients
with type 2 diabetes. However, successful long-term weight loss is difficult for these patients,
particularly those treated with insulin. The aim of this study was to assess the effect of ...
Cited by 174 - Related articles - BL Direct - All 7 versions

Effect of orlistat in overweight and obese patients with type 2 diabetes treated with …


JM Miles, L Leiter, P Hollander, T Wadden, JW … - Diabetes Care, 2002 - Am Diabetes Assoc
RESULTS—After 1 year of treatment, mean (±SE) weight loss was greater in the orlistat than
in the placebo group (−4.6 ± 0.3% vs. −1.7 ± 0.3% of baseline wt, P < 0.001). Orlistat treatment
caused a greater improvement in glycemic control than placebo, as evidenced by a ...
Cited by 172 - Related articles - BL Direct - All 7 versions

Long-term pharmacotherapy for overweight and obesity: a systematic review and …


R Padwal, SK Li, DCW Lau - International journal of obesity, 2003 - nature.com
CONTEXT: Safe and effective strategies to curb rising obesity prevalence rates are urgently needed
and medications may play a more prominent role in future therapeutic regimens. ...
OBJECTIVE: To review systematically the long-term efficacy and safety of approved ...
Cited by 317 - Related articles - BL Direct - All 10 versions

Weight control and risk factor reduction in obese subjects treated for 2 years with …


MH Davidson, J Hauptman, M DiGirolamo, JP Foreyt, … - Jama, 1999 - Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
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your experience on this site better. ... Add to CiteULike Add to Connotea Add to ...
Cited by 644 - Related articles - BL Direct - All 5 versions

Role of orlistat in the treatment of obese patients with type 2 diabetes. A 1-year …

- diabetesjournals.org [PDF] 
PA Hollander, SC Elbein, IB Hirsch, D Kelley, J … - Diabetes care, 1998 - Am Diabetes Assoc
Obesity is a significant cause of type 2 diabetes (1,2). It is also the most impo rtant modifiable
factor for this disease in both men and women (3). The incidence of type 2 diabetes rises with
inc reasing severity of obesity, and also with weight gain per se, independent of baseline ...
Cited by 545 - Related articles - BL Direct - All 6 versions

Meta-analysis: pharmacologic treatment of obesity


Z Li, M Maglione, W Tu, W Mojica, D … - Annals of internal …, 2005 - Am Coll Physicians
Background: In response to the increase in obesity, pharmacologic treatments for weight loss
have become more numerous and more commonly used. ... Purpose: To assess the efficacy
and safety of weight loss medications approved by the US Food and Drug Administration ...
Cited by 327 - Related articles - BL Direct - All 8 versions


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