- ►diabetesjournals.org G Rudofsky, P Reismann, S Witte, PM Humpert, B … - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—No difference was found between type 1 and type 2 diabetic patients in the prevalence
of alleles of the Asp299Gly and Thr399Ile polymorphisms. In most cases, the alleles Gly299 and
Ile399 occurred in a co-segregatory manner. The prevalence of the Gly299/Ile399 ... Cited by 28 - Related articles - BL Direct - All 5 versions
T Illig, F Bongardt, A Schöpfer, R Holle, S Müller, W … - Diabetes, 2003 - Am Diabetes Assoc The gene coding for the endotoxin receptor TLR4 (toll-like receptor 4) has been sequenced
recently, and the polymorphic spectrum of the gene has been elucidated (1). A polymorphism
in the gene affects the inflammatory response to lipopolysaccharide (LPS) (2,3), with ... Cited by 38 - Related articles - BL Direct - All 4 versions
P Minoretti, C Gazzaruso, CD Vito, E Emanuele, M … - Neuroscience letters, 2006 - Elsevier Experimental data have shown an upregulated expression of toll-like receptors, particularly
toll-like receptor 4 (TLR4), in neurodegeneration. The Asp299Gly polymorphism of the TLR4
gene has been associated with an attenuated receptor signalling and a blunted ... Cited by 29 - Related articles - All 4 versions
TRDJ Radstake, B Franke, S Hanssen, MG Netea, P … - Arthritis and …, 2004 - cat.inist.fr The toll-like receptor 4 Asp 299 Gly functional variant is associated with decreased
rheumatoid arthritis disease susceptibility but does not influence disease severity
and/or outcome. Timothy RDJ RADSTAKE, Barbara FRANKE ... Cited by 54 - Related articles - BL Direct - All 4 versions
Y Park, S Park, E Yoo, D Kim, H Shin - Ann NY Acad Sci, 2004 - cmbi.bjmu.edu.cn ABSTRACT: Type 1 diabetes mellitus (T1DM) is a T cell–mediated autoimmune disease in which
pancreatic ß cells are selectively destroyed. Although auto- immune diseases are driven by inappropriate
adaptive immunity, innate im- munity may play a role in the development of T1DM. We ... Cited by 28 - Related articles - View as HTML - All 8 versions
J Hang, W Zhou, H Zhang, B Sun, H Dai, L … - Journal of Endotoxin …, 2004 - ini.sagepub.com Endotoxin is an important component of bio-aerosols that contribute to airway inflammation and
airflow obstruction. Inhaled endotoxin in bio-aerosols is associ- ated with the development of
acute and chronic decline of lung function in cotton textile workers. 1 The human ... Cited by 23 - Related articles - BL Direct - All 2 versions
E Sanchez, G Orozco, MA Lopez-Nevot, J … - Tissue …, 2004 - interscience.wiley.com Abstract: Human toll-like receptors (TLRs) participate in the innate response and signal the activation
of adaptive immunity. Therefore, these TLRs may be important in autoimmune diseases such
as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). We investigated, by ... Cited by 60 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org RYL Zee, HH Hegener, J Gould, PM Ridker - Stroke, 2005 - Am Heart Assoc Results— Overall, we observed little evidence of association between the D299G polymorphism
and risk of any atherothrombotic event (P=0.25), incident MI (P=0.89), or stroke (P=0.09), assuming
an additive model. Adjusting for traditional cardiovascular risk factors or assuming a ... Cited by 37 - Related articles - All 8 versions
- ►oxfordjournals.org MK Mohammad, M Morran, B Slotterbeck, DW … - International …, 2006 - Jpn Soc Immunol The expression, responsiveness and regulation of mouse Toll-like receptors (TLRs) in bone
marrow-derived macrophages (BM-Ø) were investigated prior to and following the development
of diabetes. Expression of TLR3 and TLR5 was significantly higher in newly diabetic non- ... Cited by 24 - Related articles - BL Direct - All 8 versions
