JC Pickup - Diabetes care, 2004 - Am Diabetes Assoc There is increasing evidence that an ongoing cytokine-induced acute-phase
response (sometimes called low-grade inflammation, but part of a widespread
activation of the innate immune system) is closely involved in the ... Cited by 360 - Related articles - BL Direct - All 8 versions
H Kolb, T Mandrup-Poulsen - Diabetologia, 2005 - Springer Abstract Subclinical, low-grade systemic inflammation has been observed in
patients with type 2 diabetes and in those at increased risk of the disease.
This may be more than an epiphenomenon. Alleles of genes encoding immune/ ... Cited by 116 - Related articles - BL Direct - All 5 versions
JC Pickup - Diabetes Technology & Therapeutics, 2006 - liebertonline.com T HE FIRST CLUES that much of the patho- physiology of type 2 diabetes might be
explained by activation of the innate immune system, a cytokine-mediated
acute-phase re- sponse, and chronic low-grade inflammation stemmed from two ... Cited by 9 - Related articles - BL Direct - All 3 versions
J Spranger, A Kroke, M Möhlig, K Hoffmann, … - Diabetes, 2003 - Am Diabetes Assoc A subclinical inflammatory reaction has been shown to precede the onset of type
2 (non-insulin-dependent) diabetes. We therefore examined prospectively the
effects of the central inflammatory cytokines interleukin (IL)-1β, IL-6, ... Cited by 318 - Related articles - BL Direct - All 5 versions
BB Duncan, MI Schmidt, JS Pankow, CM … - Diabetes, 2003 - Am Diabetes Assoc To examine the association of low-grade systemic inflammation with diabetes, as
well as its heterogeneity across subgroups, we designed a case-cohort study
representing the ∼9-year experience of 10,275 Atherosclerosis Risk in ... Cited by 233 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org FB Hu, JB Meigs, TY Li, N Rifai, JAE Manson - Diabetes, 2004 - Am Diabetes Assoc We conducted a prospective, nested, case-control study of inflammatory markers
as predictors of type 2 diabetes among 32,826 women who provided blood samples
in 1989 through 1990 in the Nurses' Health Study. Among women free of ... Cited by 232 - Related articles - BL Direct - All 7 versions
MI Schmidt, BB Duncan, AR Sharrett, G … - Lancet(British edition), 1999 - cat.inist.fr Background Type 2 diabetes mellitus and atherosclerotic cardiovascular disease
have common antecedents. Since markers of inflammation predict coronary heart
disease and are raised in patients with type 2 diabetes, we investigated ... Cited by 470 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org TS Han, N Sattar, K Williams, C Gonzalez- … - Diabetes Care, 2002 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Baseline CRP, indexes of adiposity, and insulin
resistance (homeostasis model assessment [HOMA-IR]) were used to predict
development of the metabolic syndrome, defined as including two or more of ... Cited by 296 - Related articles - BL Direct - All 6 versions
A Festa, RD'Agostino, RP Tracy, SM Haffner - Diabetes, 2002 - Am Diabetes Assoc Elevated serum levels of acute-phase proteins, indicating chronic subclinical
inflammation, have been associated with cardiovascular disease as well as the
insulin resistance syndrome. Chronic inflammation may also be a risk factor ... Cited by 531 - Related articles - BL Direct - All 7 versions
M Crook - Diabetic medicine, 2004 - pt.wkhealth.com There are predictions that Type 2 diabetes mellitus could increase world wide to
over 300 million individuals within the next decade or so. A few years ago, a
hypothesis was proposed, suggesting that elements of the innate immune ... Cited by 48 - Related articles - BL Direct - All 8 versions
