- Free from Publisher ER Pearson, MK Badman, CR Lockwood, PM … - Diabetes Care, 2004 - Am Diabetes Assoc OBJECTIVE—Mutations in the highly homologous transcription factors hepatocyte
nuclear factor (HNF)-1α and -1β cause maturity-onset diabetes of the young
types 3 and 5, respectively. Diabetes due to HNF-1α mutations is well ... Cited by 33 - Related articles - BL Direct - All 6 versions
- ►oxfordjournals.org C Bingham, AT Hattersley - Nephrology Dialysis Transplantation, 2004 - ERA-EDTA Mutations in the gene encoding the transcription factor hepatocyte nuclear
factor (HNF)-1ß have recently been described in association with a variety of
abnormalities of renal development. The most consistent clinical feature is ... Cited by 42 - Related articles - BL Direct - All 4 versions
ER Pearson, MK Badmand, CR Lockwood, PM … - Diabetes Care, 2004 - Am Diabetes Assoc OBJECTIVE — Mutations in the highly homologous transcription factors
hepatocyte nuclear factor (HNF)-1 and -1 cause maturity-onset diabetes of the
young types 3 and 5, respectively. Diabetes due to HNF-1 mutations is well ... Cited by 6 - Related articles
- ►annals.org [PDF] C Bellanne-Chantelot, D Chauveau, JF Gautier, … - Annals of internal medicine, 2004 - Am Coll Physicians Setting: 2 departments of diabetes, 1 department of internal medicine, and 1
department of nephrology. Participants: 8 probands with diabetes diagnosed
before 40 years of age and nondiabetic kidney disease who were selected ... Cited by 103 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org C Bellanné-Chantelot, S Clauin, D Chauveau, … - Diabetes, 2005 - Am Diabetes Assoc Maturity-onset diabetes of the young (MODY) 5 is caused by mutations in the TCF2
gene encoding the transcription factor hepatocyte nuclear factor-1β. However,
in 60% of the patients with a phenotype suggesting MODY5, no point mutation ... Cited by 59 - Related articles - BL Direct - All 4 versions
C Bingham, S Ellard, TRP Cole, KE Jones, LIS … - Kidney international, 2002 - nature.com Renal tract malformations are, on occasion, associated with uterine
malformations. The transcription factor hepatocyte nuclear factor (HNF)-1 is
expressed from the earliest stages of development of the Wolffian duct, the ... Cited by 70 - Related articles - BL Direct - All 4 versions
- ►endojournals.org T Yorifuji, K Kurokawa, M Mamada, T Imai, M … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Mutations in the gene coding for hepatocyte nuclear factor-1ß (HNF-1ß) have
been known to cause a form of maturity-onset diabetes of the young (MODY5),
which is usually characterized by dominantly inherited adolescence-onset ... Cited by 30 - Related articles - BL Direct - All 4 versions
LW Harries, S Ellard, RWA Jones, AT … - Diabetologia, 2004 - Springer Aims/hypothesis. Mutations in the hepatocyte nuclear factor-1 beta (HNF-1β)
gene result in disorders of re- nal development, typically involving renal cysts
and early-onset diabetes (the RCAD syndrome/ MODY5). Sixteen mutations have ... Cited by 24 - Related articles - BL Direct - All 5 versions
- ►endojournals.org S Kitanaka, Y Miki, Y Hayashi, T Igarashi - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Mutations in the hepatocyte nuclear factor (HNF)-1ß lead to type 5
maturity-onset diabetes of the young (MODY5). HNF-1ß forms a homodimer or a
heterodimer with HNF-1 and regulates various target genes. HNF-1ß ... Cited by 17 - Related articles - BL Direct - All 5 versions
EL Edghill, C Bingham, AS Slingerland, JA … - Diabetic Medicine, 2006 - interscience.wiley.com Aim The transcription factor hepatocyte nuclear factor-1beta (HNF-1β) is
expressed in rodent pancreatic progenitor cells, where it is an important member
of the genetic hierarchy that regulates the generation of pancreatic ... Cited by 25 - Related articles - BL Direct - All 4 versions
