- Free from Publisher G Sesti, MA Marini, M Cardellini, A Sciacqua, … - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—Of the total patients, 53 (11.1%) were heterozygous for the Arg 972
IRS-1 variant, 1 (0.2%) was homozygous, and the remainder (88.7%) were
homozygous for the wild-type allele. The genotype frequency of the Arg 972 ... Cited by 23 - Related articles - BL Direct - All 5 versions
- ►endojournals.org G Sesti, E Laratta, M Cardellini, F Andreozzi, … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Context: Several studies suggest that genetic factors may play a role in the
different responses to antidiabetic therapy; however, conclusive evidence is
still lacking. ... Objective: The objective of the study was to ... Cited by 26 - Related articles - BL Direct - All 3 versions
G Wang, X Wang, Q Zhang, Z Ma - International Journal of Clinical Practice, 2007 - interscience.wiley.com To investigate the influence of the S447X variant in lipoprotein lipase (LPL)
gene on the response rate to therapy with the thiazolidinedione pioglitazone. A
total of 113 diabetic patients were treated with pioglitazone 30 mg for 10 ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►jbc.org AJ McGettrick, EP Feener, CR Kahn - Journal of Biological Chemistry, 2005 - ASBMB The most commonly detected polymorphism in human insulin receptor substrate-1
(IRS-1), a glycine to arginine change at codon 972 (G972R), is associated with
an increased risk of Type 2 diabetes and insulin resistance. To determine ... Cited by 21 - Related articles - All 5 versions
MJ Zychma, J Gumprecht, K Strojek, W … - Medical science monitor: international medical journal …, 2002 - ncbi.nlm.nih.gov BACKGROUND: The presence of a complex phenotype of type 2 diabetes results from
impaired insulin secretion and action, whereas the mechanism of action of
sulfonylurea derivatives, most commonly used in the treatment of type 2 ... Cited by 14 - Related articles - All 2 versions
E López-Orduña, J García-Mena, R García- … - Biochemical and Biophysical Research …, 2007 - Elsevier The mRNA concentration of CAPN10, a T2D susceptibility gene was measured in
white blood cells of T2D and healthy subjects, as well as the transcript
half-life in two SNP-43 genotyped human cell lines, to evaluate a possible ... Cited by 5 - Related articles - All 5 versions
- Free from Publisher M Blüher, G Lübben, R Paschke - Diabetes Care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—A total of 131 patients were treated in an
open-label, randomized, multicenter study with pioglitazone (45 mg od) during a
course of ≥26 weeks. Response to the pioglitazone therapy was defined by ... Cited by 43 - Related articles - BL Direct - All 5 versions
