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Scholar Results 1 - 10 of about 101 related to Ahrén: Improved meal-related β-cell function and insulin sensitivity by the dipeptidyl.... (0.13 sec) 

Improved meal-related β-cell function and insulin sensitivity by the dipeptidyl peptidase-IV …


B Ahrén, G Pacini, JE Foley, A Schweizer - Diabetes Care, 2005 - Am Diabetes Assoc
RESULTS—In subjects completing 52 weeks with participation in all meal tests
(n = 57), HbA 1c (A1C) decreased in the vildagliptin/metformin group (VM group,
n = 31) but increased in the placebo/metformin group (PM group, n = 26; ...
Cited by 178 - Related articles - BL Direct - All 9 versions

Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed {beta}-cell function …

- endojournals.org
A Mari, WM Sallas, YL He, C Watson, M … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc
Results: Vildagliptin significantly increased the insulin secretory rate at 7
mmol/liter glucose (secretory tone), calculated from the dose response; the
difference in least squares mean ( LSM) was 101 ± 51 pmol·min –1 ·m ...
Cited by 198 - Related articles - BL Direct - All 8 versions

Twelve-and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin- …


B Ahrén, R Gomis, E Standl, D Mills, A … - Diabetes Care, 2004 - Am Diabetes Assoc
RESULTS—In patients randomized to LAF237, baseline HbA 1c averaged 7.7 ± 0.1%
and decreased at week 12 (Δ = −0.6 ± 0.1%), whereas HbA 1c did not change
from a baseline of 7.9 ± 0.1% in patients given placebo (between-group ...
Cited by 313 - Related articles - BL Direct - All 8 versions

Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces …

- endojournals.org
B Ahren, M Landin-Olsson, PA Jansson, M … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
The stimulation of insulin vs. inhibition of glucagon secretion in relation to
the antidiabetic action of glucagon-like peptide-1 (GLP-1) is not established.
Here, the influence of a 4-wk increase in circulating GLP-1 by inhibition ...
Cited by 331 - Related articles - BL Direct - All 7 versions

Improved glycaemic control with dipeptidyl peptidase-4 inhibition in patients with type 2 …


S Ristic, S Byiers, J Foley, D Holmes - Diabetes Obesity and Metabolism, 2005 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 139 - Related articles - BL Direct - All 4 versions

[PDF] Twelve− week Monotherapy with the DPP− 4 Inhibitor Vildagliptin Improves Glycemic …


D Holmes - Horm Metab Res, 2006 - rima.org
The incretin hormones ± glucose−dependent insulinotropic poly− peptide
(GIP) and particularly glucagon−like peptide−1 (GLP−1) ± have been
reported to exert multiple metabolic effects that con− tribute to the ...
Cited by 120 - Related articles - View as HTML - BL Direct - All 4 versions

Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes …

- diabetesjournals.org
E Bosi, RP Camisasca, C Collober, E … - Diabetes Care, 2007 - Am Diabetes Assoc
RESULTS—The between-treatment difference (vildagliptin − placebo) in
adjusted mean change (AMΔ) ± SE in A1C from baseline to end point was −0.7
± 0.1% (P < 0.001) and −1.1 ± 0.1% (P < 0.001) in patients receiving 50 ...
Cited by 150 - Related articles - BL Direct - All 10 versions

Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in …


N Matikainen, S Mänttäri, A Schweizer, A … - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis We assessed the effects of vildagliptin, a novel
dipeptidyl peptidase IV inhibitor, on postprandial lipid and lipoprotein
metabolism in patients with type 2 diabetes. Subjects, materials and ...
Cited by 64 - Related articles - BL Direct - All 5 versions

Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase …


GA Herman, C Stevens, K Van Dyck, A … - Clinical Pharmacology & Therapeutics, 2005 - nature.com
Background: Sitagliptin (MK-0431 [(2R)-4-oxo-4-(3-[trifluoromethyl]-5,6-dihydro[
1,2,4]triazolo[4,3-a]pyrazin-7[8H]-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine])
is an orally active, potent, and selective inhibitor of dipeptidyl ...
Cited by 115 - Related articles - All 6 versions

Vildagliptin in combination with pioglitazone improves glycaemic control in patients with …


AJ Garber, A Schweizer, MA Baron, E … - Diabetes, Obesity and Metabolism, 2007 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 113 - Related articles - All 5 versions


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