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Scholar Results 1 - 10 of about 101 related to Bril: Long-term effects of ranirestat (AS-3201) on peripheral nerve function in patients.... (0.11 sec) 

Long-term effects of ranirestat (AS-3201) on peripheral nerve function in patients with …

- Free from Publisher
V Bril, RA Buchanan - Diabetes Care, 2006 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Patients with mild to moderate DSP, as determined
by the presence of sural nerve responses, were enrolled in a double-blind,
placebo-controlled biopsy trial and randomized to placebo or 5 or 20 mg/day ...
Cited by 44 - Related articles - BL Direct - All 6 versions

Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic …

- diabetesjournals.org
N Hotta, Y Akanuma, R Kawamori, K Matsuoka, … - Diabetes Care, 2006 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Subjects with diabetic neuropathy, median motor
nerve conduction velocity (MNCV) ≥40 m/s, and HbA 1c ≤9% were enrolled in
this open-label, multicenter study and randomized to 150 mg/day epalrestat ...
Cited by 46 - Related articles - BL Direct - All 5 versions

Treatment of symptomatic diabetic peripheral neuropathy with the protein kinase C β- …


AI Vinik, V Bril, P Kempler, WJ Litchy, S … - Clinical therapeutics, 2005 - Elsevier
Patients were enrolled in a multinational, randomized, Phase II, double-blind,
placebo-controlled parallel-group trial comparing 32 mg/d or 64 mg/d RBX with
placebo for 1 year. DPN was identified by abnormal measurable vibration ...
Cited by 44 - Related articles - All 3 versions

Aldose reductase inhibition by AS-3201 in sural nerve from patients with diabetic …

- Free from Publisher
V Bril, RA Buchanan - Diabetes Care, 2004 - Am Diabetes Assoc
OBJECTIVE—The primary purpose of this investigation was to determine whether
AS-3201, a new aldose reductase inhibitor, penetrates the sural nerve and
inhibits sorbitol and fructose accumulation in patients with diabetic ...
Cited by 48 - Related articles - BL Direct - All 7 versions

The effect of monochromatic infrared energy on sensation in patients with diabetic …

- diabetesjournals.org
JK Clifft, RJ Kasser, TS Newton, AJ Bush - Diabetes Care, 2005 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—In this randomized, double-blind,
placebo-controlled study, 39 subjects with diabetic peripheral neuropathy
completed the 8-week study. Subjects received 30 min of active or placebo ...
Cited by 27 - Related articles - BL Direct - All 7 versions

Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral …

- Free from Publisher
N Hotta, T Toyota, K Matsuoka, Y Shigeta, R … - Diabetes Care, 2001 - cat.inist.fr
OBJECTIVE The purpose of this study was to evaluate the efficacy of fidarestat,
a novel aldose reductase BAR) inhibitor, in a double-blind placebo controlled
study in patients with type 1 and type 2 diabetes and associated peripheral ...
Cited by 63 - Related articles - BL Direct - All 5 versions

Effective treatment of symptomatic diabetic polyneuropathy by high-frequency external …

- bolecina.com [PDF] 
L Reichstein, S Labrenz, D Ziegler, S Martin - Diabetologia, 2005 - Springer
Abstract Aims/hypothesis: Diabetic distal symmetrical sensory polyneuropathy
(DSP) affects 20–30% of diabetic patients. Transcutaneouselectricalnerve
stimulation(TENS) and electrical spinal cord stimulation have been proposed ...
Cited by 21 - Related articles - All 7 versions

Showing neuropathy is related to increased mortality in diabetic patients—a survival …


DV Coppini, PA Bowtell, C Weng, PJ Young, … - Journal of clinical epidemiology, 2000 - Elsevier
Diabetic subjects still have a reduced life expectancy despite many potential
advances in patient care. Furthermore, population-based studies in well-defined
cohorts of patients, to investigate the reduced life expectancies, are ...
Cited by 44 - Related articles - BL Direct - All 7 versions

Oral Treatment With α-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy

- diabetesjournals.org
D Ziegler, A Ametov, A Barinov, PJ Dyck, I … - Diabetes Care, 2006 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—In this multicenter, randomized, double-blind,
placebo-controlled trial, 181 diabetic patients in Russia and Israel received
once-daily oral doses of 600 mg (n = 45) (ALA600), 1,200 mg (n = 47) ...
Cited by 97 - Related articles - BL Direct - All 6 versions

Reversal of diabetic peripheral neuropathy with phototherapy (MIRETM) decreases falls and the …

- oxfordjournals.org
MW Powell, DH Carnegie, TJ Burke - Age and ageing, 2006 - Br Geriatrics Soc
Objective: to determine whether restoration of sensation, impaired due to
diabetic peripheral neuropathy (DPN), would reduce the number of falls and the
fear of falling and improve activities of daily living (ADL) in a ...
Cited by 11 - Related articles - BL Direct - All 11 versions


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