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Scholar Results 1 - 10 of about 101 related to Schön: The xylosyltransferase I gene polymorphism c. 343G> T (p. A125S) is a risk factor.... (0.10 sec) 

The xylosyltransferase I gene polymorphism c. 343G> T (p. A125S) is a risk factor …


S Schön, C Prante, C Bahr, L Tarnow, J Kuhn, K … - Diabetes care, 2006 - Am Diabetes Assoc
OBJECTIVE—Xylosyltransferase I (XT-I) is the chain-initiating enzyme in the biosynthesis of
proteoglycans in basement membranes. It catalyzes the transfer of xylose to selected serine
residues in the core protein. The XYLT-II gene codes for a protein highly homologous to ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Xylosyltransferase I variants and their impact on abdominal aortic aneurysms


C Götting, C Prante, M Schillinger, M Exner, H … - Clinica Chimica Acta, 2008 - Elsevier
The formation of abdominal aortic aneurysm (AAA) is caused by a destructive remodeling of
the extracellular matrix in the vascular wall. Proteoglycan content and biosynthesis have been
shown to be altered in AAA. Xylosyltransferase I (XT-I) is the initial and rate-limiting ...
Cited by 1 - Related articles - All 3 versions

Heterologous expression and biochemical characterization of soluble human …


JC Casanova, J Kuhn, K Kleesiek, C Götting - Biochemical and Biophysical …, 2007 - Elsevier
Human xylosyltransferase II (EC 2.4.2.26, XT-II) represents an isoform of xylosyltransferase I
(XT-I). Recently, we and others provided first evidence that XT-II is capable of initiating the biosynthesis
of glycosaminoglycan chains in proteoglycans. Here, a soluble form of human XT-II was ...
Cited by 5 - Related articles - All 4 versions

Impact of polymorphisms in the genes encoding xylosyltransferase I and a …


S SCHÖN, C Prante, S MÜLLER, M SCHÖTTLER, L … - Kidney international, 2005 - nature.com
Xylosyltransferase I (XT-I) is the chain-initiating enzyme in the biosynthesis of heparan sulfate
proteoglycans (HSPGs). It catalyses the transfer of xylose to specific serine residues in the core
protein. The XYLT-II gene codes for a protein highly homologous to the XT-I but its ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Novel sequence variants in the human xylosyltransferase I gene and their role in …


C Bahr, S Schön, J Kuhn, PH Groop, M … - Diabetic …, 2006 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
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functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 3 - Related articles - BL Direct - All 5 versions

[PDF] TGF-beta1 regulated xylosyltransferase I activity in human cardiac fibroblasts and …


C Prante, H Milting, A Kassner, M Farr, M Ambrosius, S … - J. Biol. Chem, 2007 - ASBMB
Short title : Prante et al., Xylosyltransferase I in cardiac fibrosis. ... TGF-β 1 REGULATED XYLOSYLTRANSFERASE
I ACTIVITY IN HUMAN CARDIAC FIBROBLASTS AND ITS IMPACT FOR MYOCARDIAL REMODELING
Christian Prante, Hendrik Milting*, Astrid Kassner*, Martin Farr ... & , Aly El Banayosy*, ...
Cited by 4 - Related articles - All 2 versions

Polymorphisms in the xylosyltransferase genes cause higher serum XT-I activity in …

- nih.gov
S Schon, V Schulz, C Prante, D Hendig, C Szliska, … - British Medical …, 2006 - jmg.bmj.com
Background: Pseudoxanthoma elasticum (PXE) is a heritable connective tissue disorder caused
by mutations in the ABCC6 gene. Fragmentation of elastic fibres and deposition of proteoglycans
result in a highly variable clinical picture. The altered proteoglycan metabolism suggests ...
Cited by 17 - Related articles - BL Direct - All 8 versions

Human xylosyltransferase II is involved in the biosynthesis of the uniform …

- jbc.org
C Ponighaus, M Ambrosius, JC Casanova, C … - Journal of Biological …, 2007 - ASBMB
Human xylosyltransferase I (XT-I) initiates the biosynthesis of the glycosaminoglycan (GAG) linkage
tetrasaccharide in proteoglycans. Xylosyltransferase II (XT-II) is a protein homologous to XT-I
but with hitherto unknown activity or physiological function. Here, we report the enzymatic ...
Cited by 19 - Related articles - All 6 versions

[PDF] Analyse von Glykosaminoglykanen in humanen Zellen und Körperflüssigkeiten


M Ambrosius - bieson.ub.uni-bielefeld.de
Page 1. Analyse von Glykosaminoglykanen in humanen Zellen und Körperflüssigkeiten
Dissertation zur Erlangung des naturwissenschaftlichen Doktorgrades an der Universität Bielefeld
vorgelegt von Michael Ambrosius aus Bielefeld Bielefeld / Bad Oeynhausen ...
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靶向抑制人木糖基转移酶-I 基因的 shRNA 真核表达载体的构建


石宏, 王洁, 王旭, 顾洪涛, 侯亚丽, 于利洁 - 华西口腔医学杂志, 2008 - cqvip.com
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维普资讯 中文期刊·专业文章. 维普专业检索Google学术. 临床医学 >> 华西口腔医学杂志 >>
2008年26卷2期 >> 摘要. 靶向抑制人木糖基转移酶-I基因的shRNA真核表达载体的构建. 评论推荐. ...
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