YM Cho, BS Youn, H Lee, N Lee, SS Min, SH Kwak, … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—Plasma RBP4 concentrations were higher in the IGT and type 2 diabetic groups
than in the NGT group (median 18.9 [range 11.2–45.8], 20.9 [9.9–48.5], and 18.1 μg/ml
[9.3–30.5], respectively). However, no difference was found between plasma RBP4 ... Cited by 135 - Related articles - BL Direct - All 6 versions
J Janke, S Engeli, M Boschmann, F Adams, J Böhnke, … - Diabetes, 2006 - Am Diabetes Assoc Studies in mice suggest that adipocytes serve as glucose sensors and regulate systemic glucose
metabolism through release of serum retinol-binding protein 4 (RBP4). This model has not been
validated in humans. RBP4 was highly expressed in isolated mature human adipocytes ... Cited by 146 - Related articles - BL Direct - All 6 versions
- ►shouxi.net TE Graham, Q Yang, M Bluher, A … - The New England …, 2006 - nejm.highwire.org Background Insulin resistance has a causal role in type 2 diabetes. Serum levels of retinol-binding
protein 4 (RBP4), a protein secreted by adipocytes, are increased in insulin-resistant states. Experiments
in mice suggest that elevated RBP4 levels cause insulin resistance. We sought to ... Cited by 369 - Related articles - BL Direct - All 8 versions
- ►daegu.ac.kr [PDF] TE Graham, CJ Wason, M Blüher, BB Kahn - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Levels of retinol binding protein (RBP4) are increased in the serum
of insulin-resistant human subjects even before overt diabetes develops. RBP4 levels correlate
with insulin resistance, BMI, WHR, dyslipidaemia and hypertension. Improvement of ... Cited by 69 - Related articles - BL Direct - All 6 versions
- ►endojournals.org S Gavi, LM Stuart, P Kelly, MM Melendez, DC … - Journal of Clinical …, 2007 - Endocrine Soc Objectives: The primary objective of this study was to determine whether an association between
retinol-binding protein 4 (RBP4) and insulin resistance exists in nonobese individuals without
a family history or diagnosis of diabetes. The secondary objective was to determine by a ... Cited by 58 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org N Stefan, AM Hennige, H Staiger, J Machann, F … - Diabetes Care, 2007 - Am Diabetes Assoc RESULTS—Adjusted circulating RBP4 correlated negatively with insulin sensitivity (clamp: r
= −0.33, P = 0.005; OGTT: r = −0.36, P = 0.002) and positively with parameters in the fasting state
as insulin levels (r = 0.35, P = 0.003) and homeostasis model assessment of insulin ... Cited by 77 - Related articles - BL Direct - All 7 versions
- ►endojournals.org A Yao-Borengasser, V Varma, AM Bodles, N … - Journal of Clinical …, 2007 - Endocrine Soc Design and Patients: RBP4 mRNA levels in adipose tissue and muscle of nondiabetic human
subjects with either normal or impaired glucose tolerance (IGT) were studied, along with plasma
RBP4. RBP4 gene expression was also measured in adipose tissue fractions, and from ... Cited by 56 - Related articles - BL Direct - All 4 versions
Q Yang, TE Graham, N Mody, F Preitner, OD Peroni, … - Nature, 2005 - biotech.korea.ac.kr In obesity and type 2 diabetes, expression of the GLUT4 glucose transporter is decreased selectively
in adipocytes. Adipose-specific Glut4 (also known as Slc2a4) knockout (adipose-Glut4 2 /2 )
mice show insulin resistance secondarily in muscle and liver. Here we show, using DNA ... Cited by 585 - Related articles - View as HTML - All 13 versions
- ►endojournals.org DG Haider, K Schindler, G Prager, A Bohdjalian … - Journal of Clinical …, 2007 - Endocrine Soc Results: At baseline, RBP-4 levels were markedly higher in obese than in lean subjects (2.7
± 0.5 vs. 0.9 ± 0.5 µg/ml; P < 0.001). In contrast, AGRP and obestatin were lower in obese subjects
compared with lean controls (all P < 0.001). Six months after gastric banding, BMI was ... Cited by 62 - Related articles - BL Direct - All 3 versions
N Takashima, H Tomoike, N Iwai - N Engl J Med, 2006 - hartvig.org To the Editor: Graham et al. (June 15 issue)1 report that serum levels of retinol-binding pro- tein
4 (RBP4) correlated with the magnitude of insulin resistance in various subjects. However, RBP4
and plasma insulin levels were dissociated in subjects who did not have an improvement ... Cited by 46 - Related articles - View as HTML - All 6 versions
