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Testing the accelerator hypothesis

- diabetesjournals.org
D Dabelea, RB D'Agostino, EJ Mayer-Davis, DJ … - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS—Univariately, BMI SDS was not related to age at diagnosis. In multiple linear regression,
adjusted for potential confounders, a significant interaction was found between BMI SDS and fasting
C-peptide (FCP) on onset age (P < ...
Cited by 17 - Related articles - All 2 versions

Testing the Accelerator Hypothesis: Body Size, β-Cell Function, and Age at Onset …

- diabetesjournals.org [PDF] 
TJ Wilkin - Diabetes care, 2006 - Am Diabetes Assoc
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References 1. Adams AS, Zhang F, Mah C, Grant RW, Kleinman K, Meigs JB, Ross-Degnan D: Race
differences in long-term diabetes ...
Cited by 8 - Related articles - BL Direct - All 5 versions

[CITATION] Higher body weight is associated with earlier onset of Type 1 diabetes in children: …


O Kordonouri, R Hartmann - Diabetic medicine, 2005 - cat.inist.fr
Higher body weight is associated with earlier onset of Type 1 diabetes in
children: Confirming the'Accelerator Hypothesis'. O KORDONOURI, R HARTMANN
Diabetic medicine 22:1212, 1783-1784, Blackwell, 2005.
Cited by 22 - Related articles - All 3 versions

[CITATION] DPV Scientific Initiative of Germany and Austria. The 'accelerator hypothesis': …


I Knerr, J Wolf, T Reinehr, R Stachow, M Grabert, E … - Diabetologia, 2005
Cited by 12 - Related articles

Braking the accelerator hypothesis?


JR Porter, TG Barrett - Diabetologia, 2004 - Springer
To the Editor: The accelerator hypothesis was first suggested in 2001 [1]. It postulates that Type 1
and Type 2 diabetes are not discrete but part of a spectrum of disease caused by three main
processes or accelerators; insulin ...
Cited by 23 - Related articles - BL Direct - All 4 versions

Major increase in Type 1 diabetes-no support for the Accelerator Hypothesis


MA O'connell, S Donath, FJ Cameron - Diabetic Medicine, 2007 - interscience.wiley.com
Background The Accelerator Hypothesis postulates that the apparent increase in incidence of Type 1
diabetes mellitus (T1DM) is related to an acceleration of disease onset by weight-related insulin
resistance. Our diabetes clinic has ...
Cited by 14 - Related articles - BL Direct - All 5 versions

Major increase in Type 1 diabetes: no support for the Accelerator Hypothesis


T Wilkin - Diabetic Medicine, 2008 - 万方数据资源系统
The Accelerator Hypothesis seeks to link Type 1 and Type 2 diabetes through insulin resistance, and
predicts an inverse relationship between age at onset of disease and body mass index standard
deviation score (BMI SDS) . This ...
Cited by 2 - Related articles - BL Direct - All 4 versions

Testing the accelerator hypothesis: body size, β-cell function, and age at onset of …

- diabetesjournals.org
D Dabelea - Diabetes Care, 2006 - Am Diabetes Assoc
We thank Dr. Wilkin (1) for his valuable comments. Overall, we (2) did not observe the hypothesized
association between increasing BMI and younger age at onset of diabetes among US youth with
autoimmune diabetes. Our results ...
Cited by 42 - Related articles - BL Direct - All 7 versions

The Treatment of Type 2 Diabetes Mellitus in Youth: Which Therapies?


JL Miller, JH Silverstein - Treatments in Endocrinology, 2006 - ingentaconnect.com
Type 2 diabetes mellitus in children and adolescents is becoming an increasingly important public
health Abstract concern throughout the world. This epidemic is closely associated with the increased
prevalence of obesity among youth ...
Cited by 9 - Related articles - All 3 versions

Immunomodulation for the prevention of SPIDDM and LADA


P Pozzilli, C Guglielmi - ANNALS-NEW YORK ACADEMY OF …, 2006 - interscience.wiley.com
Abstract: Type 1 diabetes may occur at any age, in young individuals before or after adolescence,
during middle age life, or even in the elderly. When diagnosed in adults it is characterized by the
presence of islet cell-related ...
Cited by 9 - Related articles - BL Direct - All 4 versions


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