- ►diabetesjournals.org S Mrena, SM Virtanen, P Laippala, P Kulmala, ML … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—A total of 47 siblings (6.7%) presented with type 1 diabetes during the 15-year observation
period. Young age, an increasing number of detectable diabetes-associated autoantibodies
at initial sampling and of affected first-degree relatives, and HLA DR–conferred disease ... Cited by 18 - Related articles - BL Direct - All 7 versions
P Xu, D Cuthbertson, C Greenbaum, JP Palmer, JP … - Diabetes Care, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Subjects (n = 186) who had a projected 25–50% risk
for diabetes and subjects (n = 170) who had a projected >50% risk for type 1 diabetes in 5 years
were followed until clinical diabetes onset or the end of the study as part of the Diabetes ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org PJ Bingley, JL Mahon, EAM Gale - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—The overall cumulative risk of diabetes within 5 years was 54.1% (95% CI
46.0–62.3). Multivariate analysis confirmed that baseline first-phase insulin response (FPIR)
quartile (P < 0.0001), number of additional antibody markers (P < 0.0001), and 120-min ... Cited by 9 - Related articles - BL Direct - All 5 versions
H Park, L Yu, T Kim, B Cho, J Kang, Y … - ANNALS-NEW YORK …, 2006 - interscience.wiley.com Abstract: Type 1 diabetes (T1D) is frequently associated with other autoimmune diseases. Most
T1D patients' sera contain two distinct glutamic acid decarboxylase (GAD) antibody
specificities, of which one targets an epitope region in the middle-third of GAD65 (amino ... Cited by 7 - Related articles - BL Direct - All 5 versions
NR Rose, CL Burek - American journal of epidemiology, 1991 - ncbi.nlm.nih.gov This brief commentary illustrates how laboratory research compliments populational
research. The finding that susceptibility to autoimmune thyroid disease in animals is due to the
additive effects of a number of unrelated genes led to a field study of a genetically ... Cited by 7 - Related articles - All 3 versions
- ►bham.ac.uk [PDF] S Fourlanos, P Narendran, GB Byrnes, PG Colman, LC … - Diabetologia, 2004 - Springer Aims/hypothesis. Glucose homeostasis is determined by an interplay between insulin secretion
and insulin action. In Type 1 diabetes, autoimmune destruction of pancreatic beta cells leads
to impaired insulin secre- tion. However, the contribution of impaired insulin ac- tion ... Cited by 76 - Related articles - BL Direct - All 6 versions
[CITATION] the DPT-1 Study Group: Pre-type 1 diabetes dysmetabolism: maximal sensitivity …
