- ►diabetesjournals.org N Stefan, AM Hennige, H Staiger, J Machann, F … - Diabetes Care, 2006 - Am Diabetes Assoc OBJECTIVE—The α 2 -Heremans-Schmid glycoprotein (AHSG; fetuin-A in animals)
impairs insulin signaling in vitro and in rodents. Whether AHSG is associated
with insulin resistance in humans is under investigation. In an animal ... Cited by 60 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] K Mori, M Emoto, H Yokoyama, T Araki, M … - Diabetes Care, 2006 - Am Diabetes Assoc To address this, we investigated the relationship of serum fetuin-A levels and
insulin resistance in nondiabetic (n = 160) and type 2 diabetic (n = 161)
subjects. Serum fetuin-A was measured by an enzyme-linked immunosorbent ... Cited by 27 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org JH Ix, MG Shlipak, VM Brandenburg, S Ali, M … - Circulation, 2006 - Am Heart Assoc Methods and Results— We defined MetS by the National Cholesterol Education
Program criteria among 711 nondiabetic outpatients with coronary artery disease.
The mean age was 67 years, and 82% were male. We divided participants into ... Cited by 46 - Related articles - All 7 versions
- ►pubget.com [PDF] F Schick - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS — AHSG plasma levels, adjusted for age, sex, and percentage of body
fat, were higher in subjects with impaired glucose tolerance compared with
subjects with normal glucose tolerance (P 0.006). AHSG plasma levels were ... Related articles - All 3 versions
- ►auburn.edu [PDF] ST Mathews, N Chellam, PR Srinivas, VJ … - Molecular and Cellular Endocrinology, 2000 - Elsevier Human fetuin, (α 2 -Heremans Schmid Glycoprotein (α 2 -HSG)], is a natural
inhibitor of insulin receptor tyrosine kinase activity (IR-TKA). Previously, we
have demonstrated that α 2 -HSG inhibits the mitogenic pathway without ... Cited by 51 - Related articles - All 5 versions
AM Hennige, H Staiger, C Wicke, F Machicao, A … - PLoS ONE, 2008 - pubmedcentral.nih.gov Human monocytic THP1 cells and human in vitro differenttiated adipocytes as well
as C57BL/6 mice were treated with fetuin-A. mRNA expression of the genes
encoding inflammatory cytokines and the adipokine adiponectin (ADIPOQ) was ... Cited by 19 - Related articles - All 6 versions
- ►shouxi.net A Siddiq, F Lepretre, S Hercberg, P Froguel, … - Diabetes, 2005 - Am Diabetes Assoc AHSG is a multifunctional protein with diverse biological functions that include
the regulation of calcium homeostasis (6,7). A possible role for AHSG in
influencing genetic susceptibility to type 2 diabetes was first suggested ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►wayne.edu [PDF] ST Mathews, GP Singh, M Ranalletta, VJ … - Diabetes, 2002 - Am Diabetes Assoc Fetuin inhibits insulin-induced insulin receptor (IR) autophosphorylation and
tyrosine kinase activity in vitro, in intact cells, and in vivo. The fetuin gene
(AHSG) is located on human chromosome 3q27, recently identified as a ... Cited by 88 - Related articles - BL Direct - All 8 versions
ST Mathews, S Rakhade, X Zhou, GC Parker, … - Biochemical and Biophysical Research …, 2006 - Elsevier Aging is associated with a metabolic decline characterized by insulin
resistance, changes in fat distribution and obesity [1] and [2]. The insulin
resistance that develops during aging has been shown to be associated with ... Cited by 18 - Related articles - All 5 versions
P Auberger, L Falquerho, JO Contreres, G … - Cell, 1989 - ncbi.nlm.nih.gov Amino acid sequence of the precursor of the phosphorylated N-glycoprotein (pp63)
secreted by rat hepatocytes was deduced from the cDNA sequence. This polypeptide
(Mr = 40,586) was rich in both cysteine and proline and contained three ... Cited by 113 - Related articles - All 4 versions