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Scholar Results 1 - 10 of about 101 related to Stefan: α2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and.... (0.10 sec) 

α2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat …

- diabetesjournals.org
N Stefan, AM Hennige, H Staiger, J Machann, F … - Diabetes Care, 2006 - Am Diabetes Assoc
OBJECTIVE—The α 2 -Heremans-Schmid glycoprotein (AHSG; fetuin-A in animals)
impairs insulin signaling in vitro and in rodents. Whether AHSG is associated
with insulin resistance in humans is under investigation. In an animal ...
Cited by 60 - Related articles - BL Direct - All 5 versions

Association of serum fetuin-A with insulin resistance in type 2 diabetic and nondiabetic …

- diabetesjournals.org [PDF] 
K Mori, M Emoto, H Yokoyama, T Araki, M … - Diabetes Care, 2006 - Am Diabetes Assoc
To address this, we investigated the relationship of serum fetuin-A levels and
insulin resistance in nondiabetic (n = 160) and type 2 diabetic (n = 161)
subjects. Serum fetuin-A was measured by an enzyme-linked immunosorbent ...
Cited by 27 - Related articles - BL Direct - All 5 versions

Association between human fetuin-A and the metabolic syndrome: data from the Heart and …

- ahajournals.org
JH Ix, MG Shlipak, VM Brandenburg, S Ali, M … - Circulation, 2006 - Am Heart Assoc
Methods and Results— We defined MetS by the National Cholesterol Education
Program criteria among 711 nondiabetic outpatients with coronary artery disease.
The mean age was 67 years, and 82% were male. We divided participants into ...
Cited by 46 - Related articles - All 7 versions

Norbert Stefan, MD Anita M. Hennige, MD Harald Staiger, PHD Jurgen Machann, PHD 2

- pubget.com [PDF] 
F Schick - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS — AHSG plasma levels, adjusted for age, sex, and percentage of body
fat, were higher in subjects with impaired glucose tolerance compared with
subjects with normal glucose tolerance (P 0.006). AHSG plasma levels were ...
Related articles - All 3 versions

α2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the …

- auburn.edu [PDF] 
ST Mathews, N Chellam, PR Srinivas, VJ … - Molecular and Cellular Endocrinology, 2000 - Elsevier
Human fetuin, (α 2 -Heremans Schmid Glycoprotein (α 2 -HSG)], is a natural
inhibitor of insulin receptor tyrosine kinase activity (IR-TKA). Previously, we
have demonstrated that α 2 -HSG inhibits the mitogenic pathway without ...
Cited by 51 - Related articles - All 5 versions

Fetuin-A induces cytokine expression and suppresses adiponectin production


AM Hennige, H Staiger, C Wicke, F Machicao, A … - PLoS ONE, 2008 - pubmedcentral.nih.gov
Human monocytic THP1 cells and human in vitro differenttiated adipocytes as well
as C57BL/6 mice were treated with fetuin-A. mRNA expression of the genes
encoding inflammatory cytokines and the adipokine adiponectin (ADIPOQ) was ...
Cited by 19 - Related articles - All 6 versions

A synonymous coding polymorphism in the α2-Heremans-Schmid glycoprotein gene is …

- shouxi.net
A Siddiq, F Lepretre, S Hercberg, P Froguel, … - Diabetes, 2005 - Am Diabetes Assoc
AHSG is a multifunctional protein with diverse biological functions that include
the regulation of calcium homeostasis (6,7). A possible role for AHSG in
influencing genetic susceptibility to type 2 diabetes was first suggested ...
Cited by 25 - Related articles - BL Direct - All 5 versions

Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene

- wayne.edu [PDF] 
ST Mathews, GP Singh, M Ranalletta, VJ … - Diabetes, 2002 - Am Diabetes Assoc
Fetuin inhibits insulin-induced insulin receptor (IR) autophosphorylation and
tyrosine kinase activity in vitro, in intact cells, and in vivo. The fetuin gene
(AHSG) is located on human chromosome 3q27, recently identified as a ...
Cited by 88 - Related articles - BL Direct - All 8 versions

Fetuin-null mice are protected against obesity and insulin resistance associated with aging


ST Mathews, S Rakhade, X Zhou, GC Parker, … - Biochemical and Biophysical Research …, 2006 - Elsevier
Aging is associated with a metabolic decline characterized by insulin
resistance, changes in fat distribution and obesity [1] and [2]. The insulin
resistance that develops during aging has been shown to be associated with ...
Cited by 18 - Related articles - All 5 versions

Characterization of a natural inhibitor of the insulin receptor tyrosine kinase: cDNA cloning, …


P Auberger, L Falquerho, JO Contreres, G … - Cell, 1989 - ncbi.nlm.nih.gov
Amino acid sequence of the precursor of the phosphorylated N-glycoprotein (pp63)
secreted by rat hepatocytes was deduced from the cDNA sequence. This polypeptide
(Mr = 40,586) was rich in both cysteine and proline and contained three ...
Cited by 113 - Related articles - All 4 versions


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