DM Kendall, CJ Rubin, P Mohideen, JM Ledeine, R … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—Analyses were conducted at week 24 for HbA 1c (A1C) and at week 12 for lipid
parameters. Mean A1C at baseline was 8.12 and 8.13% in muraglitazar and pioglitazone
groups, respectively. At week 24, muraglitazar reduced mean A1C to 6.98% (−1.14% from ... Cited by 76 - Related articles - BL Direct - All 8 versions
DM Kendall, CJ Rubin, P Mohideen, JM Ledeine, R … - Diabetes Care, 2006 - Am Diabetes Assoc A double-blind, randomized, pioglitazone-comparative study ... D AVID M. K ENDALL , MD 1
C INDY J. R UBIN , MD 2 P HARIS M OHIDEEN , MD 2 J EAN -M ARIE L EDEINE , MSC 3 R
ENE B ELDER , MD 2 J ORGE G ROSS , MD 4 P AUL N ORWOOD , MD 5 Related articles
PK Mamnoor, P Hegde, SR Datla, RKB Damarla, R … - Pharmacological …, 2006 - Elsevier Ragaglitazar is a novel and potent dual peroxisome proliferators activated receptor (PPAR) α
and γ activator. The aim of this study is to investigate the effect of ragaglitazar on blood pressure
and endothelial function in insulin resistant animal model and non-insulin resistant ... Cited by 13 - Related articles - All 6 versions
BJ Goldstein, J Rosenstock, D Anzalone, … - Current Medical …, 2006 - informahealthcare.com Objective: The Glucose and Lipid Assessment in Diabetes (GLAD) trial examined the dose-response
relationship of the dual peroxisome proliferator- activated receptor (PPAR) α/γ agonist tesaglitazar
in type 2 diabetic patients. Study design: GLAD was a 12-week, multicenter, international, ... Cited by 29 - Related articles - BL Direct - All 4 versions
- ►jhsph.edu [PDF] SE Nissen, K Wolski, EJ Topol - Jama, 2005 - Am Med Assoc Context Peroxisome proliferator–activated receptors (PPARs) are nuclear transcription factors
that modulate gene expression. Therapeutic agents targeting 2 distinct families of PPARs ( and
) have been introduced in the United States. The first dual-PPAR agonist, muraglitazar, ... Cited by 261 - Related articles - BL Direct - All 9 versions
JB Buse, CJ Rubin, R Frederich, K Viraswami-Appanna … - Clinical therapeutics, 2005 - Elsevier This was a randomized, double-blind, placebo-controlled, parallel-group, multicenter, 24-week
monotherapy study in drug-naive, type 2 diabetes patients with inadequate glycemic control.
Men and women aged 18 to 70 years with a body mass index ≤41 kg/m 2 and serum ... Cited by 65 - Related articles - All 6 versions
- ►diabetesjournals.org T Harrity, D Farrelly, A Tieman, C Chu, L Kunselman, L … - Diabetes, 2006 - Am Diabetes Assoc Muraglitazar, a novel dual ( / ) peroxisome proliferator–activated receptor (PPAR) activator, was
investigated for its antidiabetic properties and its effects on metabolic abnormalities in genetically
obese diabetic db/db mice. In db/db mice and normal mice, muraglitazar treatment ... Cited by 34 - Related articles - BL Direct - All 9 versions
P Balakumar, M Rose, SS Ganti, P Krishan, M … - Pharmacological Research, 2007 - Elsevier Cardiovascular disorders are the major cause of mortality in patients of diabetes mellitus. Peroxisome
proliferator activated receptors (PPARs) are ligand-activated transcription factors of nuclear hormone
receptor superfamily comprising of three subtypes such as PPARα, PPARγ and PPARδ/β. ... Cited by 49 - Related articles - All 3 versions
A Tenenbaum, M Motro, EZ Fisman - Cardiovascular Diabetology, 2005 - biomedcentral.com There are three peroxisome proliferator-activated receptors (PPARs) subtypes which are commonly
designated PPAR alpha, PPAR gamma and PPAR beta/delta. PPAR alpha activation increases
high density lipoprotein (HDL) cholesterol synthesis, stimulates "reverse" cholesterol ... Cited by 94 - Related articles - Cached - All 13 versions
B Fagerberg, S Edwards, T Halmos, J Lopatynski, H … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 1716–1725 DOI 10.1007/s00125-005-1846-8 ARTICLE
B. Fagerberg . S. Edwards . T. Halmos . J. Lopatynski . H. Schuster . S. Stender . G.
Stoa-Birketvedt . S. Tonstad . S Halldórsdóttir . I. Gause-Nilsson ... Cited by 72 - Related articles - All 5 versions
