- ►diabetesjournals.org LGK de Aguiar, LR Bahia, N Villela, C Laflor, … - Diabetes Care, 2006 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—The study included 31 subjects (age 38.3 ± 7.6
years and BMI 36.3 ± 5.2 kg/m 2 ), who were first-degree relatives of type 2
diabetic patients and who had metabolic syndrome and normal glucose ... Cited by 45 - Related articles - BL Direct - All 5 versions
C Vitale, G Mercuro, A Cornoldi, M Fini, M … - Journal of internal medicine, 2005 - pt.wkhealth.com Background: Metabolic Syndrome (MS) is associated with impaired endothelial
function and increased cardiovascular risk. Insulin resistance is a key feature
of MS and plays an important role in the pathogenesis of endothelial ... Cited by 51 - Related articles - BL Direct - All 6 versions
LG de Aguiar, CM Laflor, L Bahia, NR Villela, … - Diabetic Medicine, 2007 - pt.wkhealth.com Methods: Thirty normoglycaemic subjects with the metabolic syndrome (MS), who
had first-degree relatives with T2DM, participated. The mean age was 39.1 ± 8.4
years and body mass index (BMI) 35.7 ± 4.8 kg/m 2 (mean ±SD). Subjects ... Cited by 6 - Related articles - BL Direct - All 4 versions
NF Wiernsperger - Diabetes Technology & Therapeutics, 2000 - liebertonline.com T HE BIGUANIDE METFORMIN (dimethyl- biguanide) (MET) is a leading drug in the
therapy of noninsulin-dependent diabetes melli- tus (NIDDM). Over several
decades, intensive in- vestigations in experimental and clinical phar- ... Cited by 43 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org Y Hattori, K Suzuki, S Hattori, K Kasai - Hypertension, 2006 - Am Heart Assoc AMP-activated protein kinase (AMPK) is tightly regulated by the cellular AMP:ATP
ratio and plays a central role in regulation of energy homeostasis and metabolic
stress. Metformin has been shown to activate AMPK. We hypothesized that ... Cited by 54 - Related articles - All 7 versions
NF Wiernsperger, E Bouskela - Diabetes & metabolism, 2003 - ncbi.nlm.nih.gov The microvascular bed is an anatomical entity which is governed by specific,
highly regulated mechanisms which are closely adapted to the specific function
of each vascular segment. Among those, small arteriolar vasomotion and ... Cited by 44 - Related articles - BL Direct - All 2 versions
- Free from Publisher G Jörneskog, M Kalani, J Kuhl, P Båvenholm, … - Diabetes care, 2005 - Am Diabetes Assoc The pathogenesis behind diabetic microangiopathy is complex; both genetic
(1–3) and metabolic factors (4–6) are clearly of importance. Recently, it
has been demonstrated that not only patients with diabetes but also healthy ... Cited by 15 - Related articles - All 5 versions
SJ Appel, JS Harrell, ML Davenport - JOURNAL-AMERICAN ACADEMY OF NURSE …, 2005 - interscience.wiley.com 1 Susan J. Appel, PhD, APRN, BC, CCRN, is an Assistant Professor, Division of
Graduate Studies, School of Nursing, at the University of Alabama at Birmingham.
2 Joanne S. Harrell, PhD, RN, FAAN, FAHA, is a Distinguished Professor is ... Cited by 20 - Related articles - BL Direct - All 3 versions
C Albala, B Jiménez, F Pérez, C Liberman - Rev Méd Chile, 2006 - SciELO Chile The genetic components of insulin-resistance, diabetes and obesity have been
largely studied. These conditions are determined by multiple polygenic and
environmental factors. Certain candidate genes, that have common functional ... Cited by 4 - Related articles - View as HTML - All 2 versions
J Škrha, M Prázný, J Hilgertová, J Kvasnička … - European journal of clinical pharmacology, 2007 - Springer Abstract Objective Metformin may influence atherogenesis but the mechanisms are
not well understood. A pilot study was undertaken to determine whether metformin
administration is associated with changes in oxidative stress and endothe- ... Cited by 3 - Related articles - BL Direct - All 3 versions
