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Scholar Results 1 - 10 of about 101 related to Barnett: An open, randomized, parallel-group study to compare the efficacy and safety profile.... (0.14 sec) 

An open, randomized, parallel-group study to compare the efficacy and safety …


AH Barnett, M Dreyer, P Lange, M Serdarevic- … - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS—In the A1C >9.5% arm, INH demonstrated a significantly greater reduction in A1C
than metformin. Mean adjusted changes from baseline were −2.17 and −1.79%,
respectively; between-treatment difference was −0.38% (95% CI −0.63 to −0.14, P = ...
Cited by 47 - Related articles - BL Direct - All 7 versions

An open, randomized, parallel-group study to compare the efficacy and safety …

- diabetesjournals.org
AH Barnett, M Dreyer, P Lange, M Serdarevic- … - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS—Mean adjusted A1C changes from baseline were –2.03 and –1.88% in the INH and
glibenclamide groups, respectively; between-treatment difference –0.17% (95% CI –0.34 to
0.01; P = 0.058), consistent with the noninferiority criterion. In the A1C >9.5% arm, inhaled ...
Cited by 47 - Related articles - BL Direct - All 8 versions

Inhaled insulin improves glycemic control when substituted for or added to oral …

- annals.org [PDF] 
J Rosenstock, B Zinman, LJ Murphy, SC … - Annals of internal …, 2005 - Am Coll Physicians
Inhaled Insulin Improves Glycemic Control When Substituted for or ... Added to Oral Combination
Therapy in Type 2 Diabetes ... Julio Rosenstock, MD; Bernard Zinman, MD; Liam J. Murphy,
MD; Stephen C. Clement, MD; Paul Moore, MD; C. Keith Bowering, MD; Rosa Hendler, ...
Cited by 163 - Related articles - BL Direct - All 8 versions

Availability of inhaled insulin promotes greater perceived acceptance of insulin …

- diabetesjournals.org
N Freemantle, L Blonde, D Duhot, M Hompesch, R … - Diabetes Care, 2005 - Am Diabetes Assoc
Inhaled insulin (INH, Exubera) is under investigation for preprandial treatment of patients with
type 1 and type 2 diabetes (1–3). This dry-powder insulin formulation is delivered by
aerosol, permitting the noninvasive administration of rapid-acting insulin (4). Preliminary ...
Cited by 102 - Related articles - All 7 versions

The effect of smoking cessation and subsequent resumption on absorption of …

- diabetesjournals.org
RHA Becker, S Sha, AD Frick, RJ Fountaine - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS—Before smoking cessation, maximum insulin concentration (C max ) and area under
the curve (AUC) for insulin concentration time (AUC-Insulin 0–360 ) with inhaled insulin were
higher, and time to C max (t max ) shorter, in smokers than nonsmokers (C max 26.8 vs. ...
Cited by 59 - Related articles - BL Direct - All 6 versions

Inhaled insulin provides improved glycemic control in patients with type 2 diabetes …

- vcu.edu [PDF] 
SR Weiss, SL Cheng, IA Kourides, RA Gelfand, … - Archives of Internal …, 2003 - Am Med Assoc
Results At week 12, there was a significantly greater reduction in glycosylated hemoglobin for
the INH + OHA cohort (mean reduction, -2.3%) compared with the OHA-only cohort (mean
reduction, -0.1%, P<.001). Eleven patients (34%) receiving INH + OHA achieved ...
Cited by 53 - Related articles - BL Direct - All 7 versions

Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An …

- endojournals.org
SE Fineberg, T Kawabata, D Finco-Kent, C Liu, … - Journal of Clinical …, 2005 - Endocrine Soc
Research Design and Methods: Insulin antibody data from initial phase II/III trials were analyzed
comparing the efficacy and safety of inhaled insulin with various agents, including sc insulin.
Additionally, data from a 24-month extension of the phase III studies were examined. Data ...
Cited by 119 - Related articles - All 6 versions

Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous …


PA Hollander, L Blonde, R Rowe, AE Mehta, JL … - Diabetes Care, 2004 - Am Diabetes Assoc
RESULTS— HbA 1c decreased similarly in the inhaled (−0.7%) and subcutaneous (−0.6%) insulin
groups (adjusted treatment group difference: −0.07%, 95% CI −0.32 to 0.17). HbA 1c <7.0% was
achieved in more patients receiving inhaled (46.9%) than subcutaneous (31.7%) insulin ( ...
Cited by 237 - Related articles - BL Direct - All 21 versions

Time-action profile of inhaled insulin in comparison with subcutaneously injected …

- diabetesjournals.org
K Rave, S Bott, L Heinemann, S Sha, RHA Becker, … - Diabetes Care, 2005 - Am Diabetes Assoc
RESULTS—INH had a faster onset of action than both RHI and ILP, as indicated by shorter time
to early half-maximal effect (32 vs. 48 and 41 min, respectively; P < 0.001 for IHN vs. RHI and
P < 0.05 for IHN vs. ILP). Time to maximal effect was comparable between INH and ILP ...
Cited by 112 - Related articles - All 7 versions

The effect of insulin antibodies on the metabolic action of inhaled and …


T Heise, S Bott, C Tusek, JA Stephan, T Kawabata, … - Diabetes Care, 2005 - Am Diabetes Assoc
RESULTS—For the INH and SC groups, mean (±SD) IAB levels were 3.5 ± 3.9 and 2.6 ± 4.1
μU/ml at baseline, respectively, compared with 101.4 ± 140.4 and 4.3 ± 9.4 μU/ml at week
24. At week 24, the changes from baseline were similar for the INH and SC groups for ...
Cited by 80 - Related articles - BL Direct - All 6 versions


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