- ►diabetesjournals.org K Hara, M Horikoshi, T Yamauchi, H Yago, O … - Diabetes Care, 2006 - Am Diabetes Assoc OBJECTIVE—The high–molecular weight (HMW) form of adiponectin, an adipocyte-derived
insulin-sensitizing hormone, has been reported to be the most active form of this hormone. We
investigated whether measurement of plasma HMW adiponectin levels, using our newly ... Cited by 147 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org C Lara-Castro, N Luo, P Wallace, RL Klein, WT Garvey - Diabetes, 2006 - Am Diabetes Assoc Adiponectin circulates in human plasma mainly as a 180-kDa low molecular weight (LMW) hexamer
and a high molecular weight (HMW) multimer of ∼360 kDa. We comprehensively examined
the relationships between circulating levels of total adiponectin, adiponectin multimers, ... Cited by 179 - Related articles - BL Direct - All 5 versions
H Ebinuma, O Miyazaki, H Yago, K Hara, T Yamauchi, … - Clinica Chimica Acta, 2006 - Elsevier Adiponectin, an antiatherogenic adipocyte-derived protein exists in human blood as multiple
isoforms—trimeric low molecular weight (LMW), albumin-binding LMW (Alb-LMW), hexameric
middle molecular weight (MMW), and high molecular weight (HMW) forms. We developed ... Cited by 62 - Related articles - All 3 versions
M Fisher, ME Trujillo, W Hanif, AH Barnett, PG … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: It is well established that total systemic adiponectin is reduced in type
2 diabetic subjects. To date most studies have been concerned with the singular full-length protein
or proteolytically cleaved globular do- main. It is, however, apparent that the native ... Cited by 124 - Related articles - All 3 versions
Y Nakano, S Tajima, A Yoshimi, H Akiyama, M … - Journal of lipid research, 2006 - ASBMB Page 1. 1 A novel enzyme-linked immunosorbent assay specific for high-molecular weight
adiponectin. Yasuko Nakano1, Sachiko Tajima1, Ai Yoshimi1, Haruyo Akiyama2, Motoo
Tsushima3, Toshihiro Tanioka1, Takaharu Negoro1, Motowo Tomita2 and Takashi Tobe1 ... Cited by 60 - Related articles - BL Direct - All 6 versions
- ►endojournals.org R Nakashima, N Kamei, K Yamane, S … - Journal of Clinical …, 2006 - Endocrine Soc Context: Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic
adipokine. Adiponectin exists as multimers in plasma, and high molecular weight (HMW) adiponectin
is particularly thought to be the active form of the protein. ... Objective: The aim of the ... Cited by 43 - Related articles - BL Direct - All 5 versions
M Blüher, AM Brennan, T Kelesidis, J Kratzsch, M … - Diabetes Care, 2007 - Am Diabetes Assoc RESULTS—HMW adiponectin and total adiponectin (ALPCO) had similar ability to predict the
presence of insulin resistance. Total adiponectin, as measured by radioimmunoassay
(LINCO) and enzyme-linked immunosorbent assay (ELISA) (Mediagnost), correlated most ... Cited by 55 - Related articles - BL Direct - All 9 versions
R Basu, UB Pajvani, RA Rizza, PE Scherer - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Adiponectin is an adipocyte-specific secretory protein found in circulation in several
different forms and is present at significantly lower levels in the plasma of diabetic patients compared
with that of insulin-sensitive individuals. We wanted to test whether insulin per se is a ... Cited by 53 - Related articles - BL Direct - All 5 versions
H Waki, T Yamauchi, J Kamon, Y Ito, S Uchida, S … - Journal of Biological …, 2003 - ASBMB Adiponectin is an adipocyte-derived hormone, which has been shown to play important roles
in the regulation of glucose and lipid metabolism. Eight mutations in human adiponectin have
been reported, some of which were significantly related to diabetes and ... Cited by 423 - Related articles - BL Direct - All 4 versions
- ►usda.gov [PDF] MM Swarbrick, IT Austrheim-Smith, KL Stanhope, MD … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis In addition to weight loss, bariatric sur- gery for severe obesity dramatically
alleviates insulin resistance. In this study, we investigated whether circulating concentrations
of the high-molecular-weight (HMW) form of adiponectin are increased following gastric ... Cited by 48 - Related articles - All 5 versions
