- Free from Publisher P Xu, D Cuthbertson, C Greenbaum, JP Palmer … - Diabetes Care, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Subjects (n = 186) who had a projected 25–50%
risk for diabetes and subjects (n = 170) who had a projected >50% risk for type
1 diabetes in 5 years were followed until clinical diabetes onset or the ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org PJ Bingley, JL Mahon, EAM Gale - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—The overall cumulative risk of diabetes within 5 years was 54.1% (95%
CI 46.0–62.3). Multivariate analysis confirmed that baseline first-phase
insulin response (FPIR) quartile (P < 0.0001), number of additional ... Cited by 9 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org S Mrena, SM Virtanen, P Laippala, P Kulmala, … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—A total of 47 siblings (6.7%) presented with type 1 diabetes during
the 15-year observation period. Young age, an increasing number of detectable
diabetes-associated autoantibodies at initial sampling and of affected ... Cited by 18 - Related articles - BL Direct - All 7 versions
[CITATION] the European Nicotinamide Diabetes Intervention Trial (ENDIT) Group: Insulin resistance …
- Free from Publisher JP Krischer, PE Center - Diabetes Care, 2005 - Am Diabetes Assoc Received for publication 21 November 2006 and accepted in revised form 24 May
2007. ... Additional information for this article can be viewed in an online
appendix at http://care.diabetesjournals.org. ... Ping Xu 1MPH, David ... Related articles - All 2 versions
- ►bham.ac.uk [PDF] S Fourlanos, P Narendran, GB Byrnes, PG … - Diabetologia, 2004 - Springer Aims/hypothesis. Glucose homeostasis is determined by an interplay between
insulin secretion and insulin action. In Type 1 diabetes, autoimmune destruction
of pancreatic beta cells leads to impaired insulin secre- tion. However, ... Cited by 76 - Related articles - BL Direct - All 6 versions
[CITATION] the European Nicotinamide Diabetes Intervention Trial (ENDIT) Group: Progression to type 1 …
- Free from Publisher JM Sosenko, JP Palmer, CJ Greenbaum, J … - Diabetes Care, 2006 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Fifty-four DPT-1 participants (22 in the
parenteral trial and 32 in the oral trial) were studied. All had oral glucose
tolerance tests (OGTTs) at 6-month intervals from approximately 30 to 6 ... Cited by 39 - Related articles - BL Direct - All 5 versions
S Fourlanos, LC Harrison, PG Colman - Current Opinion in Endocrinology, Diabetes and …, 2008 - journals.lww.com Recent findings: Insulin resistance is an independent risk factor for
progression to clinical type 1 diabetes in people with islet autoimmunity.
Higher bodyweight is also associated with type 1 diabetes development ... Cited by 2 - Related articles - All 2 versions
- ►diabetesjournals.org [PDF] TJ Wilkin - Diabetes Care, 2008 - Am Diabetes Assoc T he accelerator hypothesis proposes that type 1 and type 2 diabetes are both
driven by insulin resistance (1), and its principle prediction is an in- verse
correlation between BMI and age at onset in children with type 1 diabetes. ... Cited by 2 - Related articles - All 4 versions