- ►diabetesjournals.org S Erbel, C Reers, VW Eckstein, J Kleeff, MW … - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—There was no significant difference between glargine and regular human
insulin with respect to regulation of proliferation and apoptosis of Colo-357
cells. The expression levels of insulin receptor, IGF-I receptor, and IRS2 ... Cited by 8 - Related articles - BL Direct - All 6 versions
E Liefvendahl, HJ Arnqvist - Hormone and Metabolic Research, 2008 - thieme-connect.com The aim of the study was to investigate if the insulin analogue glargine, with
an increased affinity for the IGF-I receptor (IGF-IR), affects the cell growth
to a larger extent than human insulin in malignant cells expressing ... Cited by 7 - Related articles - All 2 versions
D Mayer, A Shukla, H Enzmann - Archives of Physiology and Biochemistry, 2008 - informahealthcare.com Structural modification of insulin results in the generation of insulin
analogues that show altered binding affinities to the insulin receptor and/or
IGF-I receptor. As a consequence these insulin analogues may have increased ... Cited by 16 - Related articles - BL Direct - All 6 versions
- ►pubget.com [PDF] K Staiger, H Staiger, MA Schweitzer, E … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 1898–1905 DOI 10.1007/s00125-005-1874-4 ARTICLE
K. Staiger . H. Staiger . MA Schweitzer . E. Metzinger . B. Balletshofer . ... Cited by 17 - Related articles - BL Direct - All 4 versions
[CITATION] Insulin analogues display IGF-1-like mitogenic and antiapoptotic activities in cultured cancer …
P Rossetti, F Porcellati, CG Fanelli, G … - Archives of Physiology and Biochemistry, 2008 - informahealthcare.com The modern goals of insulin replacement in Type 1 and Type 2 diabetes mellitus
(T1, T2DM) are A1C <6.5% long-term, and prevention of hypoglycaemia (blood
glucose, BG <70 mg/dl). In addition to appropriate education and motivation ... Cited by 9 - Related articles - BL Direct - All 5 versions
I Zib, P Raskin - Diabetes Obesity and Metabolism, 2006 - iddtinternational.org.uk Abstract: Insulin analogues were developed to modify the structure of the human
insulin molecule in order to more accurately approximate the endogenous
secretion of insulin. With the help of recombinant technology and site- ... Cited by 11 - Related articles - View as HTML - BL Direct - All 7 versions
- ►canadianmedicaljournal.ca SR Singh, BSP MSc, F Ahmad, A Lal, C Yu, Z … - Canadian Medical Association Journal, 2009 - Can Med Assoc Methods: We updated 2 earlier systematic reviews of the efficacy and safety of
rapid-and long-acting insulin analogues. We searched electronic databases,
conference proceedings and "grey literature" up to April 2007 to identify ... Cited by 13 - Related articles - All 12 versions
K Eckardt, C May, M Koenen, J Eckel - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Mitogenic activity of insulin and insulin analogues and
the involvement of the IGF-1 receptor (IGF- 1R) is still a controversial issue.
We compared levels of the proteins IGF-1R and insulin receptor (InsR) in ... Cited by 14 - Related articles - BL Direct - All 2 versions
[CITATION] SDRN Epidemiology Group (2009) Use of insulin glargine and cancer incidence in Scotland …
