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Scholar Results 1 - 10 of about 101 related to Brown: Too much glucagon, too little insulin. (0.09 sec) 

Too much glucagon, too little insulin

- diabetesjournals.org
RJ Brown, N Sinaii, KI Rother - Diabetes Care, 2008 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Glucagon and C-peptide concentrations were determined
in response to standard mixed meals in 23 patients with type 1 diabetes aged 9.4 ± 4.6
years, beginning within 6 weeks of diagnosis, and every 3 months thereafter for 1 year.
Cited by 2 - Related articles - All 6 versions

Meal-stimulated glucagon release is associated with postprandial blood glucose …

- endojournals.org
S Porksen, LB Nielsen, A Kaas, M Kocova, F … - Journal of Clinical …, 2007 - Endocrine Soc
Endocrine Society JCEM ...
Cited by 3 - Related articles - BL Direct - All 4 versions

Glucose and C-Peptide Changes in the Perionset Period of Type 1 Diabetes in the …


JM Sosenko, JP Palmer, L Rafkin-Mervis, JP … - Diabetes Care, 2008 - Am Diabetes Assoc
RESULTS—Glucose levels increased at 90 (P = 0.006) and 120 min (P < 0.001) from the initial
diabetic OGTT to the confirmatory diabetic OGTT (mean ± SD interval 5.5 ± 2.8 weeks). Peak
C-peptide levels fell substantially between the OGTTs (median change −14.3%, P < ...
Cited by 5 - Related articles - All 3 versions

The PTPN22 1858T gene variant in type 1 diabetes is associated with reduced …

- diabetesjournals.org
A Petrone, M Spoletini, S Zampetti, M Capizzi, S … - Diabetes Care, 2008 - Am Diabetes Assoc
OBJECTIVE—Evidence has been reported for a new susceptible locus for type 1 diabetes, the
protein tyrosine phosphatase nonreceptor type 2 (PTPN22), which encodes a lymphoid-specific
phosphatase. The aim of the study was to evaluate the influence of the C1858T variant of ...
Cited by 3 - Related articles - BL Direct - All 5 versions

Human C-peptide antagonises high glucose-induced endothelial dysfunction …


P Luppi, V Cifarelli, H Tse, J Piganelli, M Trucco - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis Endothelial dysfunction in diabetes is pre- dominantly caused by hyperglycaemia
leading to vascular complications through overproduction of oxidative stress and activation of
the transcription factor nuclear factor-κB (NF-κB). Many studies have suggested that ...
Cited by 5 - Related articles - All 2 versions

[CITATION] Effects of age, duration and treatment of insulin dependent diabetes mellitus on …


The DCCT Research Group - J Clin Endocrinol Metab, 1987
Cited by 6 - Related articles

Suppressibility of glucagon secretion by glucose injuvenile diabetes+


MA Sperling, K Aleck, S Voina - The Journal of Pediatrics, 1977 - Elsevier
The suppressibility of plasma glucagon concentrations by glucose was investigated in normal
and diabetic children. Fasting concentrations of plasma glucagon were similar in normal and
in diabetic children despite the hyperglycemia of the latter. Infusion of glucose promptly ...
Cited by 6 - Related articles - All 4 versions

[CITATION] Effect of Intensive Therapy on Residual β-Cell Function in Patients with Type 1 …


EP Activity - Ann Intern Med, 1998 - Am Coll Physicians
Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the
diabetes control and complications trial. A randomized, controlled trial. The Diabetes Control
and Complications Trial Research Group Ann Intern Med 128, 517-523, 1998.
Cited by 8

Pramlintide Lowered Glucose Excursions and Was Well-Tolerated in Adolescents …


HP Chase, K Lutz, R Pencek, B Zhang, L Porter - The Journal of Pediatrics, 2009 - Elsevier
In 9 evaluable subjects, plasma pramlintide concentrations increased dose-proportionately; mean
peak plasma concentration (C max ) (15-μg dose, 93 ± 9 pg/mL; 30-μg dose, 202 ± 21
pg/mL) occurred 0.3 h (median time to peak concentration) after administration. ...
Cited by 2 - Related articles - All 18 versions

C-peptide in the natural history of type 1 diabetes


JP Palmer - Diabetes Metab Res Rev, 2009 - interscience.wiley.com
Type 1 diabetes is diagnosed when the patient's endogenous insulin secretion decreases to
a level which results in hyperglycemia. After diagnosis, insulin secretion continues to
decline. As a reference for clinical trials trying to preserve endogenous beta-cell function ...
Cited by 2 - Related articles - All 2 versions


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