- ►diabetesjournals.org SR Smith, LJ Aronne, CM Burns, NC Kesty, … - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—At month 4, mean weight loss from baseline in the pramlintide arms
ranged from 3.8 ± 0.7 to 6.1 ± 0.8 kg (2.8 ± 0.8 kg with placebo). By month
12, initial 4-month weight loss was regained in the placebo group but was ... Cited by 7 - Related articles - All 6 versions
HC Chen, JD Roth, BE Schroeder, C Weyer - Current Diabetes Reviews, 2008 - ingentaconnect.com Abstract: Contrary to its historical epithet as a lifestyle disorder, obesity is
now widely recognized as having a neurobi- ological basis. This progress is due
to our knowledge not only about energy homoeostatic pathways within the ... Cited by 6 - Related articles - All 2 versions
- ►endojournals.org JL Trevaskis, T Coffey, R Cole, C Lei, C … - Endocrinology, 2008 - Endocrine Soc Previously, we reported that combination treatment with rat amylin (100
µg/kg·d) and murine leptin (500 µg/kg·d) elicited greater inhibition of food
intake and greater body weight loss in diet-induced obese rats than ... Cited by 5 - Related articles - All 6 versions
JD Roth, H Maier, S Chen, BL Roland - Archives of Neurology, 2009 - Am Med Assoc Amylin receptor agonism is emerging as part of an integrated neurohormonal
therapeutic approach for managing diabetes mellitus (DM) and body weight.
Pramlintide acetate, an analogue of the pancreatic hormone amylin, has been ... Cited by 2 - Related articles - All 3 versions
[CITATION] Integrated neurohormonal approaches to the treatment of obesity: the amylin agonist …
JD Roth, C Mack, NC Kesty, DG Parkes, C … - Handbook of Obesity: Clinical Applications. 3rd ed. …, 2008 Cited by 4 - Related articles
- ►physiology.org SR Smith, JE Blundell, C Burns, C Ellero, … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Evidence from rodent studies indicates that the -cell-derived neurohormone
amylin exerts multiple effects on eating behavior, including reductions in meal
size, intake of highly palatable foods, and stress-induced sucrose ... Cited by 17 - Related articles - BL Direct - All 6 versions
- ►physiology.org C Mack, J Wilson, J Athanacio, J Reynolds, K … - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc The ability of amylin to reduce acute food intake in rodents is well
established. Longer-term administration in rats (up to 24 days) shows a
concomitant reduction in body weight, suggesting energy intake plays a ... Cited by 11 - Related articles - BL Direct - All 7 versions
- ►pnas.org JD Roth, BL Roland, RL Cole, JL Trevaskis, … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Body weight is regulated by complex neurohormonal interactions between endocrine
signals of long-term adiposity (eg, leptin, a hypothalamic signal) and
short-term satiety (eg, amylin, a hindbrain signal). We report that ... Cited by 31 - Related articles - BL Direct - All 6 versions
JR Robinson, KD Niswender - Current Diabetes Reports, 2009 - Springer Obesity is epidemic; new medications and therapeutic options are urgently needed
to reduce the assoc iated health care burden. The initial clinical strategy for
weight loss is lifestyle modification involving a combination of diet, ... Related articles - All 2 versions
TH Moran, MJ Dailey - Endocrinology, 2009 - Endocrine Soc Gut peptides play multiple roles in the controls of gastrointestinal function
and in the initiation and termination of meals. Plasma levels of these peptides
are differentially affected by the presence of nutrients in the digestive ... Related articles - All 2 versions
