- ►diabetesjournals.org C Herder, EJ Brunner, W Rathmann, K … - Diabetes care, 2009 - Am Diabetes Assoc OBJECTIVE—Interleukin-1 receptor antagonist (IL-1Ra), a natural inhibitor of
interleukin-1β, has been shown to improve β-cell function and glycemic control
in patients with type 2 diabetes. The aim of this study was to investigate ... Cited by 2 - Related articles - All 4 versions
- ►biologists.org S Armstrong, A Pereverzev, SJ Dixon, SM … - Journal of Cell Science, 2009 - jcs.biologists.org Nucleotides, released in response to mechanical or inflammatory stimuli, signal
through P2 nucleotide receptors in many cell types. Osteoclasts express P2X7
receptors (encoded by P2rx7) – Ca 2+ -permeable channels that are ... Cited by 3 - Related articles - All 7 versions
[CITATION] IL-1β-MyD88 signaling is central to islet chemokine secretion in response to metabolic …
SG Rønn, A Börjesson, C Bruun, PE Heding, H … - Diabetologia, 2008 - Springer Page 1. ARTICLE Suppressor of cytokine signalling-3 expression inhibits
cytokine-mediated destruction of primary mouse and rat pancreatic ... Cited by 3 - Related articles - All 2 versions
- ►nih.gov R Glas, NS Sauter, FT Schulthess, L Shu, J … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis In obesity, beta cells activate compensatory mechanisms
to adapt to the higher insulin demand. Interleukin-1 receptor antagonist
(IL-1Ra) prevents obesity- induced hyperglycaemia and is a potent target ... Cited by 1 - Related articles - All 5 versions
FT Schulthess, F Paroni, NS Sauter, L Shu, P … - Cell Metabolism, 2009 - Elsevier In type 1 and type 2 diabetes (T1/T2DM), β cell destruction by apoptosis
results in decreased β cell mass and progression of the disease. In this study,
we found that the interferon γ-inducible protein 10 plays an important ... Cited by 5 - Related articles - All 3 versions
- ►endojournals.org D Mokhtari, JW Myers, N Welsh - Endocrinology, 2008 - Endocrine Soc The aim of the present investigation was to characterize the role of the MAPK
kinase kinase-1 (MEKK-1) in stress-induced cell death of insulin producing
cells. We observed that transient overexpression of the wild type MEKK-1 ... Cited by 4 - Related articles - BL Direct - All 3 versions
- ►endojournals.org NS Sauter, FT Schulthess, R Galasso, LW … - Endocrinology, 2008 - Endocrine Soc Subclinical inflammation is a recently discovered phenomenon in type 2 diabetes.
Elevated cytokines impair β-cell function and survival. A recent clinical trial
shows that blocking IL-1β signaling by IL-1 receptor antagonist (IL-1Ra) ... Cited by 18 - Related articles - BL Direct - All 4 versions
- Free from Publisher E Ruotsalainen, U Salmenniemi, I Vauhkonen, … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—Levels of C-reactive protein and inflammatory cytokines were elevated
in nondiabetic offspring of type 2 diabetic subjects. Interleukin (IL)-1β was
increased in the NGT group and decreased in the IGT group. In contrast, ... Cited by 17 - Related articles - BL Direct - All 5 versions
