P Xu, D Cuthbertson, C Greenbaum, JP Palmer, JP … - Diabetes Care, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Subjects (n = 186) who had a projected 25–50% risk
for diabetes and subjects (n = 170) who had a projected >50% risk for type 1 diabetes in 5 years
were followed until clinical diabetes onset or the end of the study as part of the Diabetes ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org PJ Bingley, JL Mahon, EAM Gale - Diabetes Care, 2008 - Am Diabetes Assoc RESULTS—The overall cumulative risk of diabetes within 5 years was 54.1% (95% CI
46.0–62.3). Multivariate analysis confirmed that baseline first-phase insulin response (FPIR)
quartile (P < 0.0001), number of additional antibody markers (P < 0.0001), and 120-min ... Cited by 9 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org S Mrena, SM Virtanen, P Laippala, P Kulmala, ML … - Diabetes Care, 2006 - Am Diabetes Assoc RESULTS—A total of 47 siblings (6.7%) presented with type 1 diabetes during the 15-year observation
period. Young age, an increasing number of detectable diabetes-associated autoantibodies
at initial sampling and of affected first-degree relatives, and HLA DR–conferred disease ... Cited by 18 - Related articles - BL Direct - All 7 versions
[CITATION] the European Nicotinamide Diabetes Intervention Trial (ENDIT) Group: Insulin …
JP Krischer, PE Center - Diabetes Care, 2005 - Am Diabetes Assoc Received for publication 21 November 2006 and accepted in revised form 24 May 2007. ... Additional
information for this article can be viewed in an online appendix at http://care.diabetesjournals
.org. ... Ping Xu 1MPH, David Cuthbertson 1 MS, Carla Greenbaum 2MD, Jerry P. Palmer ... Related articles - All 2 versions
- ►bham.ac.uk [PDF] S Fourlanos, P Narendran, GB Byrnes, PG Colman, LC … - Diabetologia, 2004 - Springer Aims/hypothesis. Glucose homeostasis is determined by an interplay between insulin secretion
and insulin action. In Type 1 diabetes, autoimmune destruction of pancreatic beta cells leads
to impaired insulin secre- tion. However, the contribution of impaired insulin ac- tion ... Cited by 76 - Related articles - BL Direct - All 6 versions
[CITATION] the European Nicotinamide Diabetes Intervention Trial (ENDIT) Group: …
JM Sosenko, JP Palmer, CJ Greenbaum, J Mahon, … - Diabetes Care, 2006 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Fifty-four DPT-1 participants (22 in the parenteral trial
and 32 in the oral trial) were studied. All had oral glucose tolerance tests (OGTTs) at 6-month
intervals from approximately 30 to 6 months before diagnosis. The vast majority also had ... Cited by 40 - Related articles - BL Direct - All 5 versions
S Fourlanos, LC Harrison, PG Colman - Current Opinion in …, 2008 - journals.lww.com Recent findings: Insulin resistance is an independent risk factor for progression to clinical type
1 diabetes in people with islet autoimmunity. Higher bodyweight is also associated with type
1 diabetes development although no longitudinal studies have simultaneously assessed ... Cited by 2 - Related articles - All 2 versions
- ►diabetesjournals.org [PDF] TJ Wilkin - Diabetes Care, 2008 - Am Diabetes Assoc T he accelerator hypothesis proposes that type 1 and type 2 diabetes are both driven by insulin
resistance (1), and its principle prediction is an in- verse correlation between BMI and age at
onset in children with type 1 diabetes. Bingley et al. (2) examined ENDIT data and found ... Cited by 2 - Related articles - All 4 versions
