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Scholar Results 1 - 10 of about 101 related to Sarafidis: Antihypertensive therapy and the risk of new-onset diabetes. (0.10 sec) 

Antihypertensive therapy and the risk of new-onset diabetes

- diabetesjournals.org
PA Sarafidis, GL Bakris - Diabetes Care, 2006 - Am Diabetes Assoc
Numerous studies have consistently demonstrated that certain classes of antihypertensive medications
have differential effects on carbohydrate and lipid metabolism in humans. In general, higher
doses of thiazide diuretics (ie, ≥25 mg/day hydrochlorothiazide) and β-blockers, at any ...
Cited by 32 - Related articles - BL Direct - All 5 versions

Antihypertensive Medications and the Risk of Incident Type 2 Diabetes


AR Gosmanov, S Connelly, JB Lewis, NR … - Diabetes care, 2006 - Am Diabetes Assoc
Taylor et al. (1) reported that antihypertensive regimens containing either β-blockers or thiazide
diuretics confer a greater risk of new diabetes when compared with ACE inhibitors or calcium
channel blockers (CCBs). However, we feel that the interpretation of data provided by the ...
Cited by 3 - Related articles - BL Direct - All 5 versions

Antihypertensive medications and the risk of incident type 2 diabetes

- diabetesjournals.org
EN Taylor, FB Hu, GC Curhan - Diabetes Care, 2006 - Am Diabetes Assoc
RESULTS—We documented 3,589 incident cases of diabetes. After adjustment for age, BMI,
physical activity, the use of other antihypertensive medications, and other risk factors, the multivariate
relative risk (RR) of incident diabetes in participants taking a thiazide diuretic compared ...
Cited by 57 - Related articles - BL Direct - All 8 versions

Antihypertensive treatment with beta-blockers and the spectrum of glycaemic …

- oxfordjournals.org
PA Sarafidis, GL Bakris - Qjm, 2006 - Oxford Univ Press
Hypertension and type 2 diabetes mellitus (DM) are major cardiovascular risk factors, and often
cluster in the same individual in the context of the metabolic syndrome. Management of hypertension
in the diabetic patient is extremely important, and agents from all major antihypertensive ...
Cited by 23 - Related articles - BL Direct - All 8 versions

Do the metabolic effects of β-blockers make them leading or supporting …


PA Sarafidis, GL Bakris - J Clin Hypertens, 2006 - interscience.wiley.com
Reduction of blood pressure to guideline goals (ie, <130/80 mm Hg) in persons with diabetes
is crucial to optimally reduce cardiovascular events and kidney disease progression. Since many
patients will be >20/10 mm Hg above this goal, most guidelines recommend using agents ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Metabolic effects of [beta]-blockers: importance of dissociating newer from …


PA Sarafidis, GL Bakris - Journal of hypertension, 2007 - journals.lww.com
In rodent models, the ligation of both uterine arteries according to a modified method of Wigglesworth
[3] has been widely used to identify sequelae of IUGR. The original paper by Wigglesworth had
already discussed the possibility of undesired growth enhancement instead of growth ...
Cited by 4 - Related articles - BL Direct - All 3 versions

Long-term effect of diuretic-based therapy on fatal outcomes in subjects with …

- uchicago.edu [PDF] 
JB Kostis, AC Wilson, RS Freudenberger, NM … - The American journal of …, 2005 - Elsevier
Diuretic-based antihypertensive therapy is associated with the development of diabetes but with
improved clinical outcomes. It has been proposed that the duration of clinical trials has been
too short to detect the adverse effects of diabetes. We assessed the long-term mortality ...
Cited by 124 - Related articles - All 7 versions

Antihypertensive agents, insulin sensitivity, and new-onset diabetes


PA Sarafidis, SI McFarlane, GL Bakris - Current Diabetes Reports, 2007 - Springer
The effects of the antihypertensive drugs on carbohy- drate metabolism and the development
of diabetes have been a major research field for more than two decades. Many clinical studies
have investigated the effects of the antihypertensive classes on insulin sensitivity and ...
Cited by 10 - Related articles - BL Direct - All 2 versions

Differences in glucose tolerance between fixed-dose antihypertensive drug …

- diabetesjournals.org
G Bakris, M Molitch, A Hewkin, M Kipnes, P … - Diabetes Care, 2006 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—A prospective, randomized, open-label, blinded–end
points design was used to assess the effects of a T/V versus L/H combination in patients with
IGT and hypertension (n = 240) followed for up to 1 year. Doses were titrated to a systolic ...
Cited by 69 - Related articles - BL Direct - All 6 versions

State of hypertension management in the United States: confluence of risk factors …


PA Sarafidis, GL Bakris - J Clin Hypertens, 2008 - interscience.wiley.com
An improvement in the awareness and treatment of hypertension in the United States has
occurred, resulting in the best control rates in the world, which unfortunately are far below the
goals of Healthy People 2000 or 2010. This failure to achieve blood pressure (BP) goals ...
Cited by 21 - Related articles - BL Direct - All 3 versions


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