ST Bennett, AM Lucassen, SCL Gough, EE … - Nature Genetics, 1995 - nature.com The IDDM2 locus encoding susceptibility to type 1 diabetes was mapped previously
to a 4.1−kb region spanning the insulin gene and a minisatellite or variable
number of tandem repeats (VNTR) locus on human chromosome 11p15.5. By ... Cited by 531 - Related articles - All 3 versions
C Julier, RN Hyer, J Davies, F Merlin, P …, 1991 - nature.com A CLASS of alleles at the VNTR (variable number of tandem repeat) locus in the
5' region of the insulin gene (INS) on chromosome 11p is associated with
increased risk of insulin-dependent diabetes mellitus (IDDM) 1–6 , but ... Cited by 234 - Related articles - All 4 versions
AM Lucassen, C Julier, JP Beressi, C Boitard, … - Nature Genetics, 1993 - nature.com Recent studies have demonstrated that a locus at 11p15,5 confers susceptibility
to insulin dependent diabetes mellitus (IDDM). This locus has been shown to lie
within a 19 kb region. We present a detailed sequence comparison of the ... Cited by 203 - Related articles - All 2 versions
GA Hitman, AC Tarn, RM Winter, V Drummond, … - Diabetologia, 1985 - Springer Summary. A polymorphic DNA sequence in the 5'-flanking region of the human
insulin gene was studied in relation to Type 1 (insulin-dependent) diabetes. In
141 Caucasoid sub- jects analysed by Southern blot hybridisation ... Cited by 69 - Related articles - All 3 versions
- ►oxfordjournals.org L Nistico, R Buzzetti, LE Pritchard, B Van … - Human Molecular Genetics, 1996 - Oxford Univ Press Susceptibility to autoimmune insulin-dependent (type 1) diabetes mellitus is
determined by a combination of environmental and genetic factors, which include
variation in MHC genes on chromosome 6p21 (IDDM1) and the insulin gene on ... Cited by 441 - Related articles - BL Direct - All 3 versions
D Owerbach, J Nerup - Diabetes, 1982 - Am Diabetes Assoc Diabetes Skip to main page content. Home; Current Issue; Archive; Contact; Subscribe;
Alerts; Help. rss feed. Search GO. Advanced Search ». User Name Password Sign ... Cited by 97 - Related articles - All 3 versions
SC Bain, JB Prins, CM Hearne, NR Rodrigues, … - Nature Genetics, 1992 - nature.com Type 1 or insulin−dependent diabetes mellitus (IDDM) is an autoimmune disease
of the insulin−producing pancreatic −cells which is determined by both
genetic and environmental factors. The major histocompatibility complex and ... Cited by 103 - Related articles - All 2 versions
GI Bell, MJ Selby, WJ Rutter, 1982 - nature.com The sequence of the highly polymorphic region near the human insulin gene, which
begins 363 base pairs before the start of transcription and extends upstream,
indicated that it is generated by variation in the number and arrangement ... Cited by 372 - Related articles - All 3 versions
GC Kennedy, MS German, WJ Rutter - Nature genetics, 1995 - nature.com Genetic susceptibility to insulin−dependent diabetes mellitus (IDDM) is
inherited as a polygenic trait. One of the loci implicated in IDDM is a
polymorphic minisatellite 5' of the human insulin (INS) gene on chromosome ... Cited by 291 - Related articles - All 3 versions
