SS Rich - Diabetes, 1990 - Am Diabetes Assoc Research on mapping diabetes-susceptibility genes is dependent on several
factors, including the existence of a single major gene for susceptibility,
genetic homogeneity, and the existence of appropriate clinical material. ... Cited by 201 - Related articles - All 4 versions
B Newman, JV Selby, MC King, C Slemenda, … - Diabetologia, 1987 - Springer Summary. Concordance for Type 2 (non-insulin-dependent) diabetes was determined
in 250 monozygotic and 264 dizy- gotic white male twin pairs who participated in
the National Heart, Lung, and Blood Institute Twin Study. These twins were ... Cited by 292 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] SC Elbein, MD Hoffman, K Teng, MF Leppert, … - Diabetes, 1999 - Am Diabetes Assoc Considerable evidence supports a major inherited com- ponent of type 2 diabetes.
We initially conducted a genome-wide scan with 440 microsatellite markers at 10-
cM intervals in 19 multigenerational families of Northern European ancestry ... Cited by 262 - Related articles - BL Direct - All 4 versions
MM Mahtani, E Widén, M Lehto, J Thomas, M … - Nature Genetics, 1996 - nature.com Non−insulin dependent diabetes mellitus (NIDDM) affects more than 100 million
people worldwide 1,2 and is associated with severe metabolic defects, including
peripheral insulin resistance, elevated hepatic glucose production, and ... Cited by 291 - Related articles - BL Direct - All 4 versions
DW Bowden, M Sale, TD Howard, A Qadri, BJ … - Diabetes, 1997 - Am Diabetes Assoc The potential contribution of maturity-onset diabetes of the young (MODY) genes
to NIDDM susceptibility in African-American and Caucasian NIDDM-affected sibling
pairs with a history of adult-onset diabetic nephropathy has been ... Cited by 184 - Related articles - BL Direct - All 4 versions
- ►nih.gov S Ghosh, RM Watanabe, ER Hauser, T Valle, VL … - Proceedings of the National Academy of Sciences of …, 1999 - National Acad Sciences We are conducting a genome scan at an average resolution of 10 centimorgans (cM)
for type 2 diabetes susceptibility genes in 716 affected sib pairs from 477
Finnish families. To date, our best evidence for linkage is on chromosome ... Cited by 201 - Related articles - BL Direct - All 8 versions
L Ji, M Malecki, JH Warram, Y Yang, SS Rich, … - Diabetes, 1997 - Am Diabetes Assoc To test the hypothesis that a gene (or genes) in the "MODY1 region" of the long
arm of chromosome 20 contributes to the development of NIDDM, we conducted
linkage studies in 29 extended Caucasian families in which many members ... Cited by 151 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] R Duggirala, J Blangero, L Almasy, TD Dyer, … - The American Journal of Human Genetics, 1999 - Elsevier Since little is known about chromosomal locations harboring type 2
diabetes–susceptibility genes, we conducted a genomewide scan for such genes
in a Mexican American population. We used data from 27 low-income extended ... Cited by 213 - Related articles - BL Direct - All 5 versions
CL Hanis, E Boerwinkle, R Chakraborty, DL … - Nature Genetics, 1996 - nature.com Non−insulin−dependent (type 2) diabetes mellitus (NIDDM) is a common
disorder of middle−aged individuals characterized by high blood glucose levels
which, if untreated, can cause serious medical complications and lead to ... Cited by 503 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] MG Ehm, MC Karnoub, H Sakul, K Gottschalk, … - The American Journal of Human Genetics, 2000 - Elsevier Type 2 diabetes is a serious, genetically influenced disease for which no fully
effective treatments are available. Identification of biochemical or regulatory
pathways involved in the disease syndrome could lead to innovative ... Cited by 114 - Related articles - BL Direct - All 5 versions
