M Nagata, JW Yoon - Diabetes, 1992 - Am Diabetes Assoc Six CD4+ and three CD8+ islet-reactive T-cell clones were established from
lymphocytes infiltrating the pancreatic islets of NOD mice. Two of six CD4+
T-cell clones responded to NOD islet cells only, not to spleen cells. The ... Cited by 38 - Related articles - All 3 versions
[CITATION] Prospective analysis of islet lesions in BB rats
BJ Bradley, K Haskins, FG La Rosa, KJ … - Diabetes, 1992 - Am Diabetes Assoc A panel of CD4+ T-cell clones has been isolated from the spleen and lymph nodes
of diabetic NOD mice. These clones have been shown to be islet-specific both in
vivo and in vitro. One of the clones, BDC-6.9, initiates extensive damage ... Cited by 56 - Related articles - BL Direct - All 4 versions
T Utsugi, JW Yoon, BJ Park, M Imamura, N … - Diabetes, 1996 - Am Diabetes Assoc NOD mouse-derived beta-cell-specific cytotoxic T-cell (beta-CTL) clones are
diabetogenic in adult NOD mice, but only if co-injected with splenic CD4+
T-cells from diabetic animals. This investigation was initiated to ... Cited by 37 - Related articles - BL Direct - All 4 versions
M Hayakawa, K Yokono, M Nagata, N Hatamori … - Diabetes, 1991 - Am Diabetes Assoc Interactions of pancreatic islets and islet-associated mononuclear cells (IAMCs)
from the nonobese diabetic (NOD) mouse were morphologically investigated. To
obtain IAMCs, pancreatic islets isolated from adult NOD mice were cultured ... Cited by 26 - Related articles - All 4 versions
[CITATION] Studies on autoimmunity for T-cell-mediated-cell destruction: distinct difference in-cell …
M Nagata, P Santamaria, T Kawamura, T … - The Journal of Immunology, 1994 - Am Assoc Immnol Page 1. Evidence for the Role of CD8' Cytotoxic T Cells Destruction of
Pancreatic P-Cells in Nonobese Diabetic Mice' Masao Nagata ... Cited by 110 - Related articles - BL Direct - All 3 versions
K Amano, K Yokono, Y Hasegawa, T Taki, Y … - Diabetes research and clinical practice, 1995 - Elsevier Accumulated studies revealed that CD4 + T cells were initially required for
diabetes in NOD mice, whereas interaction of CD4 + T/CD8 + T cells is not fully
understood. To address this question, we established islet-derived CD4 + T ... Cited by 5 - Related articles - All 4 versions
