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Scholar Results 1 - 10 of about 101 related to Cook: Distribution of type II diabetes in nuclear families.. (0.14 sec) 

Distribution of type II diabetes in nuclear families.


JT Cook, AT Hattersley, JC Levy, P Patel, JS Wainscoat … - Diabetes, 1993 - Am Diabetes Assoc
Type II diabetes has a substantial genetic component, but the mode of inheritance and the molecular
basis of this inheritance are uncertain. This study documents the familial distribution of the disease
in the parents and siblings of a consecutive series of type II diabetic subjects. We studied ...
Cited by 14 - Related articles - BL Direct - All 5 versions

[CITATION] O, Rahilly Set al.(1993) Availability of type II diabetic families for detection of …


JTE Cook, RCL Page - Diabetes
Cited by 2 - Related articles

[CITATION] Bimodal distribution of the 2-hour blood glucose value during OGTT among first- …


H Tillil, K Richter, J Kobberting - Diabetes Res. Clin. Pract.(Suppl 1), 1985
Cited by 6 - Related articles

Analysis of three glucose transporter genes in a Caucasian population: no …


RS Oelbaum - Clinical genetics, 1992 - interscience.wiley.com
The significance of variation within the genes coding for three glucose transporter proteins in
the aetiology of non-insulin dependent diabetes mellitus was assessed by analysing restriction
fragment length polymorphisms in an English Caucasian population. Two polymorphisms ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Linkage analysis of the human insulin receptor gene in type 2 (non-insulin- …


S O'Rahilly, RC Trembath, P Patel, DJ Galton, RC … - Diabetologia, 1988 - Springer
Summary. The possibility of linkage between the human insulin receptor gene locus and diabetes
was examined in three Type 2 (non-insulin-dependent) diabetic families and one family with
maturity onset diabetes of the young. Insulin receptor gene haplotypes were established ...
Cited by 11 - Related articles - All 3 versions

Normal insulin receptors in mitochondrial myopathies with ophthalmoplegia.


G Piccolo, M Aschei, A Ricordi, P Banfi, CF Lo … - Journal of the …, 1989 - ncbi.nlm.nih.gov
Seven patients with histologically proven mitochondrial myopathy with ophthalmoplegia
(OMM), 6 of them nondiabetic, 1 affected by diabetes mellitus (DM), were submitted to a study
of glucose tolerance and of insulin receptors on peripheral mononuclear cells and ...
Cited by 11 - Related articles - All 2 versions

Insulin receptor and insulin-responsive glucose transporter (GLUT 4) mutations …


S O'Rahilly, A Krook, R Morgan, A Reese, JS Flier, DE … - Diabetologia, 1992 - Springer
Departments of Medicine and Clinical Biochemistry, University of Cambridge, Addenbrooke's
Hospital, Cambridge, 2 Department of Medicine, University ttospital of Wales, Cardiff, UK and
Department of Medicine, Beth Israel Hospital, Boston, Massachusetts, USA
Cited by 26 - Related articles - All 3 versions

Segregation analysis of NIDDM in Caucasian families


JTE Cook, DC Shields, RCL Page, JC Levy, AT … - Diabetologia, 1994 - Springer
Key words Non-insulin-dependent diabetes mellitus, genetic epidemiology, genetic linkage.
... Non-insulin-dependent diabetes mellitus (NIDDM) is a common metabolic disorder with considerable
morbidity and mortality. Despite evidence for a sub- stantial genetic component, the mode ...
Cited by 26 - Related articles - BL Direct - All 3 versions

Normal coding sequence of insulin gene in Pima Indians and Nauruans, two …


N Raben, F Barbetti, A Cama, MA Lesniak, S Lillioja, P … - Diabetes, 1991 - Am Diabetes Assoc
The nucleotide sequence of the insulin gene was determined in American Pima Indians and
Micronesian Nauruans, two populations in whom the prevalence of non-insulin-dependent (type
II) diabetes mellitus is the highest in the world. The insulin gene was amplified by the ...
Cited by 14 - Related articles - All 4 versions

[CITATION] Family Studies: Perspectives on the Genetic and Environmental Determinants of …


JR Infirmary, UK Oxford - Causes of Diabetes: Genetic and …, 1993 - John Wiley & Son Ltd
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