NK Pørksen, SR Munn, JL Steers, O Schmitz, … - Diabetes, 1996 - Am Diabetes Assoc Although sulfonylureas enhance insulin secretion, it is unknown whether these
hypoglycemic chemicals stimulate insulin secretion through the augmentation of
the pulsatile or basal modes of insulin release. Enhanced pulsatile insulin ... Cited by 26 - Related articles - BL Direct - All 5 versions
N Porksen, SR Munn, JL Steers, JD Veldhuis, … - American Journal of Physiology- Endocrinology And …, 1996 - Am Physiological Soc Porksen, Niels, Stephen R. Munn, Jeffery L. Steers, Johannes D. Veldhuis, and
Peter C. Butler. Effects of somatostatin on pulsatile insulin secretion:
selective inhibi- tion of insulin burst mass. Am. J. PhysioZ. 270 ... Cited by 33 - Related articles - BL Direct - All 4 versions
N Porksen, S Munn, J Steers, JD Veldhuis, PC … - Diabetes, 1996 - Am Diabetes Assoc In the present studies, we used a recently validated canine model to determine
1) if glucose ingestion stimulates insulin secretion by amplifying the pulsatile
component of insulin release, and if so, 2) whether this effect is achieved ... Cited by 43 - Related articles - BL Direct - All 5 versions
N Pørksen, B Grøfte, B Nyholm, JJ Holst, SM … - Diabetes, 1998 - Am Diabetes Assoc Glucagon-like peptide 1 (GLP-1) is a peptide hormone that is released from the
gut after luminal stimulation. The hormone is a potent insulin secretagogue and
is a potential novel pharmaceutical adjuvant in the treatment of NIDDM. ... Cited by 30 - Related articles - BL Direct - All 5 versions
O Schmitz, SB Pedersen, A Mengel, N … - Metabolism, 1994 - Elsevier The present study was designed to examine the effect of pulsatile versus
continuous insulin delivery on glucose and lipid metabolism in insulin-resistant
subjects. Six obese women (body mass index, 40.0 ± 2.8 kg/m 2 ) underwent ... Cited by 20 - Related articles - BL Direct - All 5 versions
- ►physiology.org N Porksen, B Nyholm, JD Veldhuis, PC Butler … - American Journal of Physiology- Endocrinology And …, 1997 - Am Physiological Soc Detection of insulin secretory bursts in peripheral blood is hampered by hepatic
insulin extraction, dilution in the systemic insulin pool, and time-delayed
damping of secretory burst amplitude. Previous studies in dogs in vivo and ... Cited by 68 - Related articles - BL Direct - All 3 versions
- ►physiology.org [PDF] N Porksen, MA Hussain, TL Bianda, B Nyholm, … - American Journal of Physiology- Endocrinology And …, 1997 - Am Physiological Soc IGF-I inhibits burst mass of pulsatile insulin secretion ... NIELS P@RKSEN,l
MEHBOOB A. HUSSAIN,2 TL BIANDA,2 ... BIRGIT NYHOLM,l JENS S. CHRISTIANSEN,l
PETER C. BUTLER,3 ... JOHANNES D. VELDHUIS,4 E. RUDI FROESCH,2 AND OLE ... Cited by 25 - Related articles - All 3 versions
N Porksen, S Munn, J Steers, S Vore, J … - American Journal of Physiology- Endocrinology And …, 1995 - Am Physiological Soc Page 1. Pulsatile insulin secretion accounts for 70% of total insulin secretion
during fasting NIELS PaRKSEN, STEPHEN MUNN, JEFFERY STEERS, ... Cited by 72 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] N Pørksen, S Munn, D Ferguson, T O'Brien, J … - Journal of Clinical Investigation, 1994 - pubmedcentral.nih.gov Intraportal transplantation of pancreatic islets is a therapeutic option under
active investigation for patients with insulin-de- pendent diabetes mellitus
(1-4). Intrahepatic autotransplanta- tion of pancreatic islets salvaged ... Cited by 27 - Related articles - All 4 versions
N Porksen, S Munn, J Steers, JD Veldhuis, PC … - American Journal of Physiology- Endocrinology And …, 1995 - Am Physiological Soc INSULIN, LIKE THE hypothalamopituitary hormones, is secreted in a pulsatile
manner (4, 18). However, in contrast to pituitary hormones, the optimal sampling
intensity, duration, and vascular site for insulin have not been fully ... Cited by 27 - Related articles - BL Direct - All 3 versions
