C Cailleau, A Diu-Hercend, E Ruuth, R Westwood, C … - Diabetes, 1997 - Am Diabetes Assoc Interleukin-1 (IL-1) has been shown to be involved in the pathogenesis of IDDM, but it is not clear
which form, IL-1alpha or IL-1beta, is predominantly implicated. In this study, we have evaluated
the contribution of IL-1beta by treating diabetes-prone nonobese diabetic (NOD) mice ... Cited by 40 - Related articles - BL Direct - All 4 versions
F Nicoletti, R Di Marco, W Barcellini, G … - European journal of …, 1994 - interscience.wiley.com We have evaluated the effects of a treatment with soluble interleukin-1 receptor (sIL-1R) in the
accelerated model of autoimmune diabetes induced by cyclophosphamide (CY) in the non-obese
diabetic (NOD) mouse. Prior to the CY challenge (350 mg/kg body weight), female ... Cited by 45 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] JO Sandberg, DL Eizirik, S Sandler - Clinical and Experimental …, 1997 - pubmedcentral.nih.gov SUMMARY The effect of an IL-1 receptor antagonist on recurrence of hyperglycaemia after syngeneic
pancreatic islet transplantation to spontaneously diabetic female NOD mice was
investigated. The transplanted animals were treated with either the receptor antagonist ... Cited by 37 - Related articles - BL Direct - All 5 versions
[CITATION] Immunohistochemical analyses of pancreatic macrophages and CD4 and CD8 T …
A Rabinovitch, W Suarez-Pinzon, A El-Sheikh, O … - Diabetes, 1996 - Am Diabetes Assoc Cytokines produced by islet-infiltrating mononuclear leukocytes may be involved in islet
beta-cell destruction and IDDM. To determine which cytokine(s) might be involved in islet
beta-cell destruction, we used a reverse transcriptase-polymerase chain reaction assay to ... Cited by 57 - Related articles - BL Direct - All 5 versions
F Nicoletti, P Zaccone, R Di Marco, M Di Mauro, G … - Endocrinology, 1996 - Endocrine Soc Page 1. oom7227/96/$03.00/O Endocrinology CopyrIght 0 1996 by The Endocrine Society Vol.
137, No. 12 Printed in USA The Effects of a Nonimmunogenic Form of Murine Soluble
Interferon-y Receptor on the Development of Autoimmune Diabetes in the NOD Mouse ... Cited by 42 - Related articles - BL Direct - All 4 versions
T Tabatabaie, AM Vasquez, DR Moore, RA Floyd, Y … - Pancreas, 2001 - journals.lww.com Introduction: Proinflammatory cytokines may play a pivotal role in the pathogenesis of
insulin-dependent diabetes mellitus (IDDM). In vitro, the formation of nitric oxide (NO) catalyzed
by inducible NO synthase (iNOS) has been shown to be involved in the cytotoxic effects of ... Cited by 10 - Related articles - BL Direct - All 3 versions
H Rothe, RM O'hara, S Martin, H Kolb - Diabetologia, 1997 - Springer The disease process in diabetes prone nonobese dia- betic (NOD) mice can be accelerated
by a single in- jection of cyclophosphamide (CY). Concomitantly, early peri-insular infiltration
of islets progress to destructive intra-insulitis [1–3]. At the immunoregu- latory level a shift ... Cited by 62 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] M Arnush, MR Heitmeier, AL Scarim, MH … - Journal of Clinical …, 1998 - pubmedcentral.nih.gov Resident macrophages have been suggested to participate in the initiation of cell damage during
the development of autoimmune diabetes. The purpose of this study was to de- termine if the
endogenous production and release of inter- leukin 1 (IL-1) in human islets of ... Cited by 116 - Related articles - BL Direct - All 6 versions
A Rabinovitch, WL Suarez-Pinzon, O Sorensen, RC … - Endocrinology, 1996 - Endocrine Soc Page 1. 0013.7227/96/$0:3 00/O Endocnnolo&y Copyright 0 1996 hy The Endocrine Socvzty
Vol. 137, No. 5 Prmtcd ,n US A. Inducible Nitric Oxide Synthase (iNOS) in Pancreatic Islets of
Nonobese Diabetic Mice: Identification of iNOS= Expressing Cells and Relationships ... Cited by 99 - Related articles - BL Direct - All 3 versions
