- ►diabetesjournals.org [PDF] K Tsuruzoe, E Araki, N Furukawa, T Shirotani … - Diabetes, 1998 - Am Diabetes Assoc It has been proposed that mitochondrial oxidative phosphorylation in pancreatic
-cells plays an impor- tant role in insulin secretion. To examine the impact of
mitochondrial dysfunction on insulin secretion, we created a MIN6 cell line ... Cited by 45 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] ED Kennedy, P Maechler, CB Wollheim - Diabetes, 1998 - Am Diabetes Assoc Mitochondrial dysfunction due to alterations in the mitochondrial genome (mtDNA)
has recently attracted much attention, with the finding that mutations in the
mitochondrially encoded proteins perturb cell func- tion. Several disorders ... Cited by 82 - Related articles - BL Direct - All 5 versions
A Soejima, K Inoue, D Takai, M Kaneko, H … - Journal of Biological Chemistry, 1996 - ASBMB To determine whether mtDNA and mitochondrial respiratory function in pancreatic
beta cells are necessary for the phenotypic expression of glucose-stimulated
insulin secretion, we used a cultured mouse pancreatic beta cell line, ... Cited by 90 - Related articles - All 6 versions
L ImpairedInsulinSecretionInducedbyGlucose - DIABETES, 1998 - Am Diabetes Assoc It has been proposed that mitochondrial oxidative phosphorylation in pancreatic
-cells plays an impor- tant role in insulin secretion. To examine the impact of
mitochondrial dysfunction on insulin secretion, we created a MIN6 cell line ... Related articles
T Hayakawa, M Noda, K Yasuda, H Yorifuji, S … - Journal of Biological Chemistry, 1998 - ASBMB Recently, a mitochondrial mutation was found to be associated with maternally
inherited diabetes mellitus (Kadowaki, T., Kadowaki, H., Mori, Y., Tobe, K.,
Sakuta, R., Suzuki, Y., Tanabe, Y, Sakura, H., Awata, T., Goto, Y., ... Cited by 51 - Related articles - BL Direct - All 5 versions
- ►unige.ch [PDF] B Lee, PD Miles, L Vargas, P Luan, S Glasco … - Diabetes, 2003 - Am Diabetes Assoc The mitochondrial Na + -Ca 2+ exchanger (mNCE) mediates efflux of Ca 2+ from
mitochondria in exchange for influx of Na + . We show that inhibition of the
mNCE enhances mitochondrial oxidative metabolism and increases glucose- ... Cited by 21 - Related articles - BL Direct - All 5 versions
P Maechler - Cellular and molecular life sciences, 2002 - Springer Abstract. Mitochondrial metabolism is crucial for the coupling of glucose
recognition to the exocytosis of the insulin granules. This is illustrated by in
vitro and in vivo observations discussed in the present review. Mitochon- ... Cited by 43 - Related articles - BL Direct - All 5 versions
JA Maassen, E Van Essen, JM Van den … - Experimental and Clinical Endocrinology and Diabetes, 2001 - thieme-connect.com This review provides a compact overview on the contribution of mutations in
mtDNA to the pathogenesis of diabetes mellitus, with emphasis on the A3243G
mutation in the tRNA(Leu,UUR) gene. This mutation associates in most ... Cited by 31 - Related articles - BL Direct - All 4 versions
P Maechler, CB Wollheim - Nature, 2001 - maechler.unige.ch The aetiology of type 2, or non-insulin-dependent, diabetes mellitus has been
characterized in only a limited number of cases. Among these, mitochondrial
diabetes, a rare subform of the disease, is the consequence of pancreatic ... Cited by 194 - Related articles - View as HTML - BL Direct - All 9 versions
P Rorsman - Diabetologia, 1997 - Springer The central role of ions in the control of cellular excit- ability has been
recognized for more than a century and dates back to the pioneering work of
Ringer [1]. For a long time, electrical excitability was a property ... Cited by 180 - Related articles - BL Direct - All 3 versions
