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negative feedback to the brain to inhibit body fat accumulation. This protein is
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M Nishiyama, S Makino, K Asaba, K … - Journal of neuroendocrinology, 1999 - interscience.wiley.com The product of the ob gene, leptin, is thought to act in the hypothalamus to
reduce food intake and body weight (bw) in rats and mice; however, the
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S Okamoto, K Kimura, M Saito - Neuroscience letters, 2001 - Elsevier Leptin is a key afferent signal that decreases food intake and increases energy
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AP Goldstone, JG Mercer, I Gunn, KM Moar, … - FEBS letters, 1997 - Elsevier The adipose tissue hormone, leptin, and the neuropeptide glucagon-like peptide-1
(7–36) amide (GLP-1) both reduce food intake and body weight in rodents. Using
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