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Hypothalamic orexin expression: modulation by blood glucose and feeding.

- diabetesjournals.org [PDF] 
XJ Cai, PS Widdowson, J Harrold, S Wilson, RE … - Diabetes, 1999 - Am Diabetes Assoc
Orexins (hypocretins), novel peptides expressed in specific neurons of the lateral hypothalamic
area (LHA), stimulate feeding when injected intracere- broventricularl y. We investigated their
role in feeding in the rat by measuring hypothalamic prepro-orexin mRNA levels under ...
Cited by 159 - Related articles - BL Direct - All 4 versions

Insulin-induced hypoglycemia increases preprohypocretin (orexin) mRNA in the rat …


B Griffond, PY Risold, C Jacquemard, C Colard, D … - Neuroscience letters, 1999 - Elsevier
The recent identification of two peptides named hypocretins (Hcrt), and expressed in neurons
of the rat tuberal lateral hypothalamus (LHA) previously detected by an ovine prolactin
antiserum, led us to revisit some experimental procedures intented to understand the ...
Cited by 119 - Related articles - All 6 versions

Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are …


T Moriguchi, T Sakurai, T Nambu, M Yanagisawa, K … - Neuroscience letters, 1999 - Elsevier
Orexin-A and -B (also known as hypocretin-1 and -2) are neuropeptides which stimulate food
intake when administered intracerebroventricularly. Orexins are specifically localized in neurons
within and around the lateral hypothalamic area (LHA). Previous electrophysiological ...
Cited by 143 - Related articles - All 5 versions

Hypoglycemia activates orexin neurons and selectively increases hypothalamic …

- diabetesjournals.org
XJ Cai, ML Evans, CA Lister, RA Leslie, JRS Arch, S … - Diabetes, 2001 - Am Diabetes Assoc
Orexins are novel appetite-stimulating peptides expressed in the lateral hypothalamic area
(LHA), and their expression is stimulated by hypoglycemia in fasted rats. We investigated activation
of orexin and other neurons during insulin-induced hypoglycemia using the immediate ...
Cited by 104 - Related articles - BL Direct - All 4 versions

[PDF] Hypothalamic Orexin Expression


MB GlucoseandFeeding - DIABETES, 1999 - Am Diabetes Assoc
Orexins (hypocretins), novel peptides expressed in specific neurons of the lateral hypothalamic
area (LHA), stimulate feeding when injected intracere- broventricularl y. We investigated their
role in feeding in the rat by measuring hypothalamic prepro-orexin mRNA levels under ...
Related articles

Effects of single and chronic intracerebroventricular administration of the orexins …


AC Haynes, B Jackson, P Overend, RE Buckingham, S … - Peptides, 1999 - ncbi.nlm.nih.gov
Two novel hypothalamic neuropeptides, orexin-A and -B, are suggested to regulate feeding.
A single intracerebroventricular injection of orexin-A (23.4 nmol), administered 3 h into the light
phase, increased feeding in satiated rats and prolonged feeding in fasted rats; it also ...
Cited by 169 - Related articles - All 4 versions

Feeding response to central orexins


DC Sweet, AS Levine, CJ Billington, CM Kotz - Brain research, 1999 - Elsevier
Fig. 1. Orexin A in the PFH. Bars represent 2 h food intake of rats injected with orexin A in the
PFH. Asterisk (*) indicates significant difference from saline controls (p<0.001). Rats injected
with 5 and 250 pmol did not eat, therefore no bar is depicted in the graph.
Cited by 178 - Related articles - All 4 versions

Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the …

- cjb.net
TL Horvath, S Diano, AN van den Pol - Journal of Neuroscience, 1999 - neuro.cjb.net
Hypocretin (orexin) has recently been shown to increase feeding when injected into the
brain. Using both rat and primate brains, we tested the hypothesis that a mechanism of hypocretin
action might be related to synaptic regulation of the neuropeptide Y (NPY) system. ...
Cited by 278 - Related articles - BL Direct - All 5 versions

The effect of the orexins on food intake: comparison with neuropeptide Y, melanin- …

- endocrinology-journals.org [PDF] 
CM Edwards, S Abusnana, D Sunter, KG … - Journal of …, 1999 - Soc Endocrinology
Journal of Endocrinology (1999) 160, R7–R12 Accepted 15 January 1999 0022-0795/99/0160
-00R7 © 1999 Society for Endocrinology Printed in Great Britain ... Online version via
http://www.endocrinology.org ... The effect of the orexins on food intake: comparison with ...
Cited by 225 - Related articles - BL Direct - All 10 versions

Chronic intracerebroventricular administration of orexin-A to rats increases food …


A Yamanaka, T Sakurai, T Katsumoto, M Yanagisawa, … - Brain research, 1999 - Elsevier
Orexins are recently identified neuropeptides, and have been shown to increase food intake
when administered intracerebroventricularly. We examined the effects of chronic administration
of orexin in rats by continuous intracerebroventricular administration by means of an ...
Cited by 100 - Related articles - All 4 versions


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