- ►diabetesjournals.org [PDF] H Sakamaki, S Akazawa, M Ishibashi, K … - Diabetes, 1999 - Am Diabetes Assoc Hyperglycemia-induced embryonic malformations may be due to an increase in
radical formation and depletion of intracellular glutathione (GSH) in embryonic
tissues. In the past, we have investigated the role of the glutathione- ... Cited by 66 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] P Wentzel, N Welsh, UJ Eriksson - Diabetes, 1999 - Am Diabetes Assoc Previous experimental studies suggest that diabetic embryopathy is associated
with an excess of radical oxy- gen species (ROS), as well as with a disturbance
of prostaglandin (PG) metabolism. We aimed to investigate the relationship ... Cited by 81 - Related articles - BL Direct - All 5 versions
UJ Eriksson, CM Siman - Diabetes, 1996 - Am Diabetes Assoc The increased incidence of congenital malformations in diabetic pregnancy may be
associated with an excess of free oxygen radicals in the embryo. We have
previously blocked the dysmorphogenesis of rat embryos exposed to high ... Cited by 71 - Related articles - BL Direct - All 6 versions
E Sivan, EA Reece, YK Wu, CJ Homko, M … - American journal of obstetrics and gynecology, 1996 - Elsevier Study Design: Eighty-day-old Sprague-Dawley rats were assigned to one of five
groups: two control groups (groups 1 and 2) and three diabetic groups (groups 3,
4, and 5). One group of controls (group 2) and one group of diabetic rats ... Cited by 79 - Related articles - BL Direct - All 5 versions
Y Yamaguchi, S Goto, Y Urata, T Kondo, S … - DIABETES, 1999 - Am Diabetes Assoc Hyperglycemia-induced embryonic malformations may be due to an increase in
radical formation and depletion of intracellular glutathione (GSH) in embryonic
tissues. In the past, we have investigated the role of the glutathione- ... Related articles
CM Siman, UJ Eriksson - Diabetologia, 1997 - Springer Although improved metabolic control of maternal di- abetes has reduced the rate
of complications during pregnancy, the incidence of congenital malformations is
still increased in children of insulin-dependent-dia- betic (IDDM) mothers ... Cited by 70 - Related articles - BL Direct - All 4 versions
P Wentzel, UJ Eriksson - DIABETES-NEW YORK-, 1998 - Am Diabetes Assoc Previous studies have suggested that the metabolism of arachidonic acid and
radical oxygen species (ROS) are altered in diabetes and that these disturbances
may induce severe embryonic dysmorphogenesis in diabetic pregnanc y. We ... Cited by 57 - Related articles - BL Direct - All 5 versions
R Piddington, J Joyce, P Dhanasekaran, L … - Diabetologia, 1996 - Springer Summary The arachidonic acid cascade leading to prostaglandins has been
implicated in diabetic em- bryopathy. Both arachidonic acid and prostaglandin E
2 reverse the teratogenic effects of high glucose con- centrations on ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►physiology.org [PDF] X Yang, LA Borg, UJ Eriksson - American Journal of Physiology- Endocrinology And …, 1997 - Am Physiological Soc MATERNAL METABOLIC disturbances in diabetic preg- nancy, in particular
hyperglycemia, have a detrimental effect on embryonic development (29). An
increased incidence of congenital malformations has been found in the ... Cited by 54 - Related articles - BL Direct - All 5 versions
