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Scholar Results 1 - 10 of about 101 related to Sindelar: Low plasma leptin levels contribute to diabetic hyperphagia in rats. (0.10 sec) 

Low plasma leptin levels contribute to diabetic hyperphagia in rats

- diabetesjournals.org [PDF] 
DK Sindelar, PJ Havel, RJ Seeley, CW … - Diabetes, 1999 - Am Diabetes Assoc
The adipocyte hormone leptin reduces food intake in normal animals. During
uncontrolled type 1 diabetes, plasma leptin levels fall, whereas food intake in-
creases. To test the hypothesis that low leptin levels contribute to ...
Cited by 64 - Related articles - BL Direct - All 4 versions

Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by …

- physiology.org
PJ Havel, JY Uriu-Hare, T Liu, KL Stanhope, … - … Journal of Physiology- Regulatory, Integrative and …, 1998 - Am Physiological Soc
Evidence for regulation of circulating leptin by insulin is conflicting.
Diabetes was induced in rats with streptozotocin (STZ; 40 mg · kg 1 · day 1 ×
2 days) to examine the effect of insulin-deficient diabetes and insulin ...
Cited by 77 - Related articles - BL Direct - All 3 versions

Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic …

- diabetesjournals.org [PDF] 
PJ Havel, TM Hahn, DK Sindelar, DG Baskin, … - Diabetes, 2000 - Am Diabetes Assoc
Hypothalamic melanocortins are among several neu- ropeptides strongly implicated
in the control of food intake. Agonists for melanocortin 4 (MC-4) receptors such
as -melanocyte–stimulating hormone ( -MSH), a product of ...
Cited by 66 - Related articles - BL Direct - All 5 versions

Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic …


AJ Sipols, DG Baskin, MW Schwartz - Diabetes, 1995 - Am Diabetes Assoc
To test the hypothesis that diabetic hyperphagia results from insulin deficiency
in the brain, diabetic rats (streptozotocin-induced) were given an
intracerebroventricular (ICV) infusion of saline or insulin (at a dose that ...
Cited by 203 - Related articles - BL Direct - All 5 versions

[CITATION] Leptin production and action: relevance to energy balance in humans

- ajcn.org [PDF] 
PJ Havel - American Journal of Clinical Nutrition, 1998 - Am Soc Nutrition
The cloning of the gene responsible for obesity in the ob/ob mouse in 1994 and
the resulting discovery of leptin (1) has spawned a flurry of investigation into
the biology of this novel adipocyte hormone, with > 600 papers currently in ...
Cited by 38 - Related articles - BL Direct - All 3 versions

[PDF] Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in …


N Chinookoswong, JL Wang, ZQ Shi… - DIABETES-NEW YORK-, 1999 - Am Diabetes Assoc
Leptin has been shown to improve insulin sensitivity and glucose metabolism in
normoinsulinemic healthy or obese rodents. It has not been determined whether
leptin may act independently of insulin in regulating energy metabolism in ...
Cited by 84 - Related articles - BL Direct - All 4 versions

Some characteristics of feeding during streptozotocin-induced diabetes in the rat


DA Booth - J Comp Physiol Psychol, 1972 - psycnet.apa.org
At 4-9 days after streptozotocin injection (50 mg/kg) rats show abbreviated
intermeal intervals. There is also a lack of proportionality of intermeal in-
terval duration to size of the preceding meal, which probably accounts for ...
Cited by 42 - Related articles - All 4 versions

Intracisternal insulin alters sensitivity to CCK-induced meal suppression in baboons


DP Figlewicz, LJ Stein, D West, D Porte Jr, … - … Journal of Physiology- Regulatory, Integrative and …, 1986 - Am Physiological Soc
9 other HighWire hosted articles, the first 5 are: This article has been cited
by ... [PDF] [Full Text] [Abstract] , December 1, 2001; 226 (11): 963-977.
Experimental Biology and Medicine PJ Havel Long-Term Regulation of Food ...
Cited by 42 - Related articles - All 3 versions

The house economist and the eating paradox


SC Woods - Appetite, 2002 - Elsevier
An important observation of the experiments of George Collier is that animals
normally prefer to maintain their body weight by eating a large number of small
meals each day. However, as the effort to obtain access to food increases, ...
Cited by 8 - Related articles - BL Direct - All 6 versions

Serum leptin levels during cancer chemotherapy


K Usuki, R Okazaki, S Iki, M Muramatsu, Y … - Annals of Hematology, 1998 - Springer
Cancer chemotherapy induces anorexia by stimulation of serotonin, dopamine,
histamine, and acetylcholine secretion [2]. Leptin, the adipocyte-specific
product of the ob gene, regulates food intake [3, 4]. We measured serum ...
Related articles - BL Direct - All 3 versions


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