- ►diabetesjournals.org [PDF] EJ Kurth-Kraczek, MF Hirshman, LJ Goodyear, WW … - Diabetes, 1999 - Am Diabetes Assoc It has previously been reported that exercise causes an increase in glucose uptake in skeletal
muscle and also an increase in 5 AMP–activated protein kinase (AMPK) activit y.
5-Aminoimidazole-4-carboxamide-1- - D - ribof u- ranoside (AICA-riboside), an analog of ... Cited by 322 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] T Hayashi, MF Hirshman, EJ Kurth, WW Winder, LJ … - Diabetes, 1998 - Am Diabetes Assoc The intracellular signaling proteins that lead to exer- cise-stimulated glucose transport in skeletal
muscle have not been identified, although it is clear that there are sep- arate signaling mechanisms
for exercise- and insulin- stimulated glucose transport. We have hypothesized that the 5 ... Cited by 474 - Related articles - BL Direct - All 4 versions
- ►physiology.org GF Merrill, EJ Kurth, DG Hardie, WW … - American Journal of …, 1997 - Am Physiological Soc 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) has previously been reported to be
taken up into cells and phosphorylated to form ZMP, an analog of 5'-AMP. This study was designed
to determine whether AICAR can activate AMP-activated protein kinase (AMPK) in ... Cited by 394 - Related articles - BL Direct - All 5 versions
R Bergeron, RR Russell III, LH Young, JM … - American Journal of …, 1999 - Am Physiological Soc The effect of AMP-activated protein kinase (AMPK) activation on skeletal muscle glucose metabolism
was examined in awake rats by infusing them with 5-aminoimidazole-4-carboxamide 1- -D-ribofuranoside
(AICAR; 40 mg/kg bolus and 7.5 mg · kg 1 · min 1 constant infusion) along with a variable ... Cited by 189 - Related articles - BL Direct - All 4 versions
- ►physiology.org BF Holmes, EJ Kurth-Kraczek, WW … - Journal of Applied …, 1999 - Am Physiological Soc This study was designed to determine whether chronic chemical activation of AMP-activated
protein kinase (AMPK) would increase glucose transporter GLUT-4 and hexokinase in muscles
similarly to periodic elevation of AMPK that accompanies endurance exercise training. ... Cited by 255 - Related articles - BL Direct - All 5 versions
J Mu, JT Brozinick, O Valladares, M Bucan, MJ … - Molecular cell, 2001 - cell.com Eukaryotic cells possess systems for sensing nutritional stress and inducing compensatory mechanisms
that minimize the consumption of ATP while utilizing alternative energy sources. Such stress
can also be imposed by increased energy needs, such as in skeletal muscle of exercising ... Cited by 485 - Related articles - All 7 versions
T Hayashi, MF Hirshman, N Fujii, SA Habinowski, LA … - Diabetes, 2000 - Am Diabetes Assoc 5 AMP-activated protein kinase (AMPK) can be acti- vated in response to cellular fuel depletion
and leads to switching off ATP-consuming pathways and switching on ATP-regenerating pathways
in many cell types. We have hypothesized that AMPK is a central mediator of insulin- ... Cited by 244 - Related articles - BL Direct - All 6 versions
WW Winder, DG Hardie - American Journal of Physiology- …, 1996 - Am Physiological Soc Page 1. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein
kinase in muscle during exercise WW WINDER AND DG HARDIE Zoology Department,
Brigham Young University, Provo, Utah 84602; and ... Cited by 363 - Related articles - BL Direct - All 3 versions
D Vavvas, A Apazidis, AK Saha, J Gamble, A Patel, … - Journal of Biological …, 1997 - ASBMB The concentration of malonyl-CoA, a negative regulator of fatty acid oxidation, diminishes acutely
in contracting skeletal muscle. To determine how this occurs, the activity and properties of
acetyl-CoA carboxylase β (ACC-β), the skeletal muscle isozyme that catalyzes ... Cited by 280 - Related articles - BL Direct - All 4 versions
N Fujii, T Hayashi, MF Hirshman, JT Smith, SA … - … and biophysical research …, 2000 - Elsevier The 5′AMP-activated protein kinase (AMPK) is stimulated by contractile activity in rat skeletal
muscle. AMPK has emerged as an important signaling intermediary in the regulation of cell metabolism
being linked to exercise-induced changes in muscle glucose and fatty acid metabolism. In ... Cited by 186 - Related articles - BL Direct - All 5 versions
