- ►diabetesjournals.org [PDF] JD Trudeau, JP Dutz, E Arany, DJ Hill, WE … - Diabetes, 2000 - Am Diabetes Assoc In neonatal rodents, the -cell mass undergoes a phase of remodeling that
includes a wave of apoptosis. Using both mathematical modeling and histochemical
detec- tion methods, we have demonstrated that -cell apo- ptosis is ... Cited by 153 - Related articles - BL Direct - All 4 versions
JD Trudeau, JP Dutz, E Arany, DJ Hill, WE … - Diabetes, 2000 - Am Diabetes Assoc In neonatal rodents, the -cell mass undergoes a phase of remodeling that
includes a wave of apoptosis. Using both mathematical modeling and histochemical
detec- tion methods, we have demonstrated that -cell apo- ptosis is ... Cited by 1 - Related articles
- ►diabetesjournals.org BA O'Brien, Y Huang, X Geng, JP Dutz, DT … - Diabetes, 2002 - Am Diabetes Assoc Macrophages limit inflammatory responses by clearing apoptotic cells.
Deficiencies in apoptotic cell phagocytosis have been linked to autoimmunity. In
this study, we determined the efficiency with which macrophages from ... Cited by 67 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org Y Zhang, B O'Brien, J Trudeau, R Tan, P … - The Journal of Immunology, 2002 - Am Assoc Immnol CTLs are important mediators of pancreatic cell destruction in the nonobese
diabetic mouse model of type 1 diabetes. Cross-presentation of Ag is one means
of priming CTLs. The death of Ag-bearing cells has been implicated in ... Cited by 66 - Related articles - BL Direct - All 3 versions
P Hoglund, J Mintern, C Waltzinger, W Heath, … - Journal of Experimental Medicine, 1999 - jem.rupress.org Little is known about the events triggering lymphocyte invasion of the
pancreatic islets in prelude to autoimmune diabetes. For example, where
islet-reactive T cells first encounter antigen has not been identified. We ... Cited by 233 - Related articles - BL Direct - All 7 versions
BA O'Brien, WE Fieldus, CJ Field, DT … - Cell death and differentiation, 2002 - ncbi.nlm.nih.gov The kinetics of beta-cell death in neonatal diabetes-prone (BBdp) and
diabetes-resistant (BBdr) BioBreeding rats was investigated using both direct
(histochemical) and indirect (mathematical modelling) techniques. In both ... Cited by 27 - Related articles - BL Direct - All 2 versions
D Mathis, L Vence, C Benoist… - Nature, 2001 - nature.com Discovered in the late 1970s, the non-obese diabetic (NOD) mouse has become the
most commonly used animal model of autoimmune diabetes 2 . Disease develops
spontaneously in this strain, sharing several crucial features with the ... Cited by 358 - Related articles - BL Direct - All 6 versions
- ►rupress.org S Turley, L Poirot, M Hattori, C Benoist, D … - Journal of Experimental Medicine, 2003 - jem.rupress.org The prelude to type-1 diabetes is leukocyte infiltration into the pancreatic
islets, or insulitis. This process begins in pancreatic lymph nodes when T
lymphocytes reactive to islet ß cells encounter antigen-presenting cells ... Cited by 143 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] SA Kassem, I Ariel, PS Thornton, I Scheimberg … - Diabetes, 2000 - Am Diabetes Assoc Hyperinsulinism of infancy (HI), also known as persis- tent hyperinsulinemic
hypoglycemia of infancy, is a rare genetic disorder that occurs in ~1 of 50,000
live births. Histologically, pancreases from HI patients can be divided ... Cited by 111 - Related articles - BL Direct - All 5 versions
- ►rupress.org MC Gagnerault, JJ Luan, C Lotton, F Lepault - Journal of Experimental Medicine, 2002 - jem.rupress.org Nonobese diabetic (NOD) mice develop spontaneous autoimmune diabetes that
results from the destruction of insulin secreting ß cells by diabetogenic T
cells. The time and location of the encounter of autoantigen(s) by naive ... Cited by 94 - Related articles - BL Direct - All 6 versions
