- ►diabetesjournals.org [PDF] S Seewaldt, HE Thomas, M Ejrnaes, U … - Diabetes, 2000 - Am Diabetes Assoc Autoimmune diabetes is caused by selective loss of insulin-producing pancreatic
-cells. The main factors directly implicated in -cell death are autoreactive,
cytotoxic (islet-antigen specific) T-lymphocytes (CTL), and inflammatory ... Cited by 74 - Related articles - BL Direct - All 5 versions
- ►t-online.de [PDF] MCDTI Cytokines - DIABETES, 2000 - Am Diabetes Assoc Autoimmune diabetes is caused by selective loss of insulin-producing pancreatic
-cells. The main factors directly implicated in -cell death are autoreactive,
cytotoxic (islet-antigen specific) T-lymphocytes (CTL), and inflammatory ... Related articles - All 2 versions
MG Von Herrath, J Dockter, MB Oldstone - Immunity, 1994 - ncbi.nlm.nih.gov We developed two distinct transgenic mouse models in which virus induced
insulin-dependent (type 1) diabetes mellitus (IDDM). In one of these lines, the
unique viral transgene was expressed in the islets of Langerhans and also ... Cited by 187 - Related articles - All 2 versions
M von Herrath, A Holz - Journal of Autoimmunity, 1997 - Elsevier RIP-LCMV transgenic mice that express the viral glycoprotein (GP) or
nucleoprotein (NP) from lymphocytic choriomeningitis virus (LCMV) under control
of the rat insulin promoter (RIP) in pancreatic β-cells develop autoimmune ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org U Christen, T Wolfe, U Mohrle, AC Hughes, E … - The Journal of Immunology, 2001 - Am Assoc Immnol We report here that islet-specific expression of TNF- can play a dual role in
autoimmune diabetes, depending on its precise timing in relation to the ongoing
autoimmune process. In a transgenic model (rat insulin promoter-lymphocytic ... Cited by 89 - Related articles - BL Direct - All 3 versions
- ►jimmunol.org U Christen, DB McGavern, AD Luster, MG von … - The Journal of Immunology, 2003 - Am Assoc Immnol Infection of the pancreas with lymphocytic choriomeningitis virus results in
rapid and differential expression among CXCR3 chemokines. IFN- -inducible
protein of 10 kDa (IP-10), in contrast with monokine induced by IFN- and ... Cited by 65 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org A Holz, T Dyrberg, W Hagopian, D Homann, M … - The Journal of Immunology, 2000 - Am Assoc Immnol We evaluated the role of the humoral arm of the immune response in causing or
contributing to virus-induced diabetes. Transgenic mice expressing the
nucleoprotein (NP) or glycoprotein (GP) of the lymphocytic choriomeningitis ... Cited by 18 - Related articles - BL Direct - All 2 versions
MG Von Herrath, S Guerder, H Lewicki, RA … - Immunity, 1995 - ncbi.nlm.nih.gov We evaluated the role of the costimulatory molecule B7-1 in overcoming
peripheral ignorance in transgenic mice, which expressed the glycoprotein (GP)
or nucleoprotein (NP) of lymphocytic choriomeningitis virus (LCMV) as the ... Cited by 134 - Related articles - BL Direct - All 2 versions
- ►nih.gov B Coon, LL An, JL Whitton, MG von Herrath - Journal of Clinical Investigation, 1999 - Am Soc Clin Investig Mice expressing lymphocytic choriomeningitis virus nucleoprotein (LCMV-NP) as a
transgene in their β cells develop insulin-dependent diabetes mellitus (IDDM)
only after LCMV infection. Inoculation of plasmid DNA encoding the insulin ... Cited by 84 - Related articles - BL Direct - All 8 versions
- ►nih.gov [PDF] N Sevilla, D Homann, M von Herrath, F … - Journal of Virology, 2000 - Am Soc Microbiol Virus-specific cytotoxic T lymphocytes (CTL) at frequencies of >1/1,000 are
sufficient to cause insulin-dependent diabetes mellitus (IDDM) in transgenic
mice whose pancreatic cells express as "self" antigen a protein from a ... Cited by 29 - Related articles - BL Direct - All 6 versions
