S De Cosmo, A Argiolas, G Miscio, S Thomas … - DIABETES-NEW …, 2000 - Am Diabetes Assoc Insulin resistance characterizes type 1 diabetes in patients with albuminuria. A PC-1 glycoprotein
amino acid variant, K121Q, is associated with insulin resis- tance. We examined the impact of
the PC-1 K121Q vari- ant on the rate of decline of the glomerular filtration rate (GFR) by ... Cited by 38 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org P Jacobsen, N Grarup, L Tarnow, HH Parving, O … - Nephrology Dialysis …, 2002 - ERA-EDTA Results. Patients carrying the Q allele had a mean rate of decline in GFR during follow-up of
3.6 ml/min per year (SE 0.4) compared with 4.0 ml/min per year (SE 0.3) in patients with the KK
genotype. Other risk factors for progression of diabetic nephropathy were similar in Q ... Cited by 16 - Related articles - BL Direct - All 4 versions
LH Canani, DPK Ng, A Smiles, JJ Rogus, JH Warram, … - Diabetes, 2002 - Am Diabetes Assoc A polymorphism in the ecto-nucleotide pyrophosphatase/phosphodiesterase 1 gene
(ENPP1) (previously known as PC-1), resulting in an amino acid change from lysine to glutamine
at codon 121 (K121Q), is associated with insulin resistance. A small follow-up study of ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org L Tarnow, N Grarup, T Hansen, HH Parving, O … - Nephrology Dialysis …, 2001 - ERA-EDTA Background. An XbaI polymorphism in the gene encoding the glucose transporter, GLUT-1, is
associated with development of diabetic nephropathy in Chinese type 2 diabetic patients. In
addition, an amino acid variant (K121Q) in the gene encoding the glycoprotein plasma ... Cited by 23 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org SD Cosmo, G Miscio, L Zucaro, M Margaglione, A … - Nephrology Dialysis …, 2002 - ERA-EDTA Background. The DD genotype of the ACE gene predisposes to faster diabetic nephropathy
(DN) progression but its role in DN development is more controversial. We reported
previously, in type 1 diabetic patients, an association between faster DN progression and ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] SK Rasmussen, SA Urhammer, A Pizzuti, SM Echwald, … - Diabetes, 2000 - Am Diabetes Assoc The human plasma-cell membrane differentiation anti- gen-1 (PC-1) has been shown to inhibit
insulin receptor tyrosine kinase activity. Recently, a K121Q polymor- phism in the human
PC-1 gene was found in a Sicilian population and was shown to be strongly associated ... Cited by 67 - Related articles - BL Direct - All 4 versions
S De Cosmo, M Margaglione, V Tassi, M … - Diabetes/Metabolism … - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 15 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org S De Cosmo, R Trevisan, M Dalla Vestra, M … - Diabetes care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—A total of 125 patients with type 2 diabetes and abnormal
albumin excretion rate (AER) (range 20–5,416 μg/min) were followed up for 4 years with repeated
measurements of glomerular filtration rate (GFR). Genomic DNA was extracted from all ... Cited by 13 - Related articles - BL Direct - All 5 versions
BV Costanzo, V Trischitta, R Di Paola, D Spampinato, A … - Diabetes, 2001 - Am Diabetes Assoc When overexpressed, the membrane glycoprotein PC-1 may play a role in human insulin resistance
through the inhibition of insulin receptor (IR) autophosphorylation. A PC-1 variant (K 121 Q, with
lysine 121 replaced by glutamine) is also associated with whole-body insulin resistance ... Cited by 76 - Related articles - BL Direct - All 5 versions
A Pizzuti, L Frittitta, A Argiolas, R Baratta, ID … - DIABETES-NEW …, 1999 - Am Diabetes Assoc The genes responsible for insulin resistance are poorly defined. Plasma cell differentiation antigen
(PC-1) gly- coprotein inhibits insulin receptor signaling and is associated with insulin
resistance. We describe here a novel polymorphism in exon 4 of the PC-1 gene (K121Q) ... Cited by 147 - Related articles - BL Direct - All 5 versions
