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Scholar Results 1 - 10 of about 101 related to Serreze: Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting.... (0.12 sec) 

Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical …


DV Serreze, EW Ottendorfer, TM Ellis, CJ … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc
Coxsackievirus infections have been proposed as an environmental trigger for the
development of T-cell–mediated autoimmune (type 1) diabetes by either
providing a molecular mimic of the candidate pancreatic -cell autoantigen ...
Cited by 82 - Related articles - BL Direct - All 5 versions

Requirements for Viral-mediated Autoimmune Diabetes: β-Cell Damage and Immune …


MS Horwitz, C Fine, A Ilic, N Sarvetnick - Journal of Autoimmunity, 2001 - Elsevier
The induction of autoimmunity by viruses has been attributed to numerous
mechanisms. Coxsackievirus B4 (CB4) induces insulin-dependent diabetes mellitus
(IDDM) in mice resembling the final step of disease progression in humans. ...
Cited by 26 - Related articles - BL Direct - All 4 versions

T-cell responses to enterovirus antigens in children with type 1 diabetes


S Juhela, H Hyoty, M Roivainen, T Harkonen, A … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc
Enterovirus infections, implicated in the pathogenesis of type 1 diabetes in a
number of studies, may precipi- tate the symptoms of clinical diabetes and play
a role in the initiation of the -cell damaging process. The aim of this ...
Cited by 49 - Related articles - BL Direct - All 4 versions

Presented antigen from damaged pancreatic β cells activates autoreactive T cells in virus …

- nih.gov
MS Horwitz, A Ilic, C Fine, E Rodriguez, N … - Journal of Clinical Investigation, 2002 - Am Soc Clin Investig
The induction of autoimmunity by viruses has been attributed to numerous
mechanisms. In mice, coxsackievirus B4 (CB4) induces insulin-dependent diabetes
mellitus (IDDM) resembling the final step of disease progression in humans. ...
Cited by 83 - Related articles - BL Direct - All 6 versions

Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin- …

- nih.gov
S Tracy, KM Drescher, NM Chapman, KS Kim, … - Journal of Virology, 2002 - Am Soc Microbiol
Insulin-dependent (type 1) diabetes mellitus (T1D) onset is mediated by
individual human genetics as well as undefined environmental influences such as
viral infections. The group B coxsackieviruses (CVB) are commonly named as ...
Cited by 51 - Related articles - BL Direct - All 9 versions

Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides …

- direct-ms.org [PDF] 
NC Schloot, SJM Willemen, G Duinkerken, JW … - Human Immunology, 2001 - Elsevier
Type 1 diabetes mellitus is a T-cell mediated autoimmune disease in which the
insulin-producing pancreatic beta cells are selectively destroyed. Molecular
mimicry and T-cell crossreactivity to β-cell autoantigens and ...
Cited by 39 - Related articles - BL Direct - All 4 versions

Enterovirus variants in the serum of children at the onset of type 1 diabetes mellitus


C Nairn, DN Galbraith, KW Taylor, GB … - Diabetic Medicine, 1999 - interscience.wiley.com
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display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 69 - Related articles - BL Direct - All 4 versions

Mechanisms of Coxsackievirus-induced damage to human pancreatic {beta}-cells

- endojournals.org
M Roivainen, S Rasilainen, P Ylipaasto, R … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc
Enteroviruses may be involved in the pathogenesis of insulin-dependent diabetes
mellitus, either through direct ß-cell infection or as triggers of
autoimmunity. In the present study we investigated the patterns of ...
Cited by 91 - Related articles - BL Direct - All 4 versions

Association between rotavirus infection and pancreatic islet autoimmunity in children at risk …


MC Honeyman, BS Coulson, NL Stone, SA … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc
Pancreatic islet autoimmunity leading to type 1 dia- betes could be triggered by
viruses in genetically sus- ceptible individuals. Rotavirus (RV), the most
common cause of childhood gastroenteritis, contains peptide sequences ...
Cited by 165 - Related articles - BL Direct - All 6 versions

Coxsackieviral-mediated diabetes: induction requires antigen-presenting cells and is …


MS Horwitz, A Ilic, C Fine, B Balasa, N … - Clinical Immunology, 2004 - Elsevier
Epidemiological studies have associated coxsackie B virus (CBV) with the
development of insulin-dependent diabetes mellitus (IDDM) in humans. Infections
of genetically susceptible mice with CBV strain 4 (CB4) induce autoimmune ...
Cited by 20 - Related articles - All 3 versions


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