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Scholar Results 1 - 10 of about 101 related to Overbergh: 1alpha, 25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper.... (0.08 sec) 

1alpha, 25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T- …

- diabetesjournals.org [PDF] 
L Overbergh, B Decallonne, M Waer, O Rutgeerts, D … - Diabetes, 2000 - Am Diabetes Assoc
Prevention of type 1 diabetes in NOD mice by 1,25- dihydroxyvitamin D3 [1 ,25(OH)2D3] is accompanied
by a T-helper (Th) 1/Th2 cytokine shift in the pancreas. The aim of this study was to investigate
whether this immune shift also ...
Cited by 37 - Related articles - BL Direct - All 7 versions

[PDF] Autoantigen-Specific T-helper 1/T-helper 2 Immune Shift in NOD Mice Immunized …


L Overbergh, B Decallonne, M Waer, O Rutgeerts, D … - Diabetes, 2000 - Am Diabetes Assoc
(5 µg/kg every 2 days) or control vehicle were immunized with GAD65 (p524–543) or ovalbumin (OVA)
in the rear footpads. First, we examined T-cell proliferation and cytokine production (via
enzyme-linked immunosorbent assay) ...
Cited by 15 - Related articles

1α, 25-Dihydroxyvitamin D3 or analogue treated dendritic cells modulate human …


AGS van Halteren, OM Tysma, E van Etten, C … - Journal of Autoimmunity, 2004 - Elsevier
Epidemiological evidence indicates that the vitamin D status after birth modulates the risk for
development of type 1 diabetes mellitus (T1DM). We previously demonstrated that the biologically
active form of vitamin D, 1α,25- ...
Cited by 31 - Related articles - All 6 versions

Prevention of type I diabetes in nonobese diabetic mice by late intervention with …

- endojournals.org
KM Casteels, C Mathieu, M Waer, D Valckx, L … - Endocrinology, 1998 - Endocrine Soc
In nonobese diabetic (NOD) mice, type I diabetes can be prevented without generalized
immunosuppression by nonhypercalcemic analogs of vitamin D 3 when treatment is started early, ie
before the autoimmune attack, ...
Cited by 78 - Related articles - BL Direct - All 5 versions

1, 25-Dihydroxyvitamin D3 restores sensitivity to cyclophosphamide-induced …


K Casteels, M Waer, R Bouillon, J … - Clinical and …, 1998 - pubmedcentral.nih.gov
The activated form of vitamin D, 1,25(OH) 2 D 3 , and its analogues can prevent type I diabetes in
NOD mice. Protection is achieved without signs of systemic immunosuppression and is associated with
a restoration of the defective ...
Cited by 51 - Related articles - BL Direct - All 7 versions

1 alpha, 25-Dihydroxycholecalciferol reduces rejection and improves survival in rat …


CA Redaelli, M Wagner, YH Tien, L … - Hepatology (Baltimore, …, 2001 - ncbi.nlm.nih.gov
Vitamin D(3) affects the immuno response and improves experimental autoimmune diseases. We
investigated the effect of 1,25-dihydroxycholecalciferol (1,25[OH](2)D(3)) Rocaltrol as a single
immunosuppressive agent and in ...
Cited by 24 - Related articles - BL Direct - All 5 versions

Identification and immune regulation of 25-hydroxyvitamin D-1-α-hydroxylase in …


L Overbergh, B Decallonne, D Valckx, A … - Clinical and …, 2000 - pubmedcentral.nih.gov
Receptors for 1,25(OH) 2 vitaminD 3 are found in most immune cells and important immunological
effects have been described in vitro, reflected by its capacity to prevent autoimmunity and to
prolong graft survival. The aim of ...
Cited by 72 - Related articles - BL Direct - All 6 versions

Association between vitamin D receptor genotype and age of onset in juvenile …

- diabetesjournals.org [PDF] 
I Yokota, S Satomura, S Kitamura, Y Taki, E Naito, … - Diabetes care, 2002 - Am Diabetes Assoc
1,25-dihydroxyvitamin D3[1,25(OH)2D3] not only regulates calcium metabolism but also modulates the
immune system. Some reports have suggested that 1,25(OH)2D3 helps to prevent the devel- opment of
type 1 diabetes. The associa- tion ...
Cited by 21 - Related articles - BL Direct - All 5 versions

Nuclear factor of activated T cells (NFAT) as a molecular target for 1 {alpha}, 25- …

- jimmunol.org
A Takeuchi, GS Reddy, T Kobayashi, T … - The Journal of …, 1998 - Am Assoc Immnol
The molecular basis of the immunomodulatory properties of 1 ,25-dihydroxyvitamin D 3 (1 ,25(OH) 2 D
3 ) remains elusive. We demonstrate here that 1 ,25(OH) 2 D 3 -mediated suppressive effects on the
inducible expression of cytokine ...
Cited by 90 - Related articles - All 4 versions

Vitamin D~ 3: a transcriptional modulator of the interferon- gene


M Cippitelli, A Santoni - European journal of immunology, 1998 - interscience.wiley.com
1 ,25-Dihydroxyvitamin D 3 [1 2 25-(OH) 2 D 3 ] exerts several effects on the immune system, by
regulating lymphocyte proliferation, differentiation of monocytes and secretion of cytokines as
IL-2, granulocyte-macrophage colony- ...
Cited by 112 - Related articles - BL Direct - All 5 versions


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