- ►diabetesjournals.org C Bonny, A Oberson, S Negri, C Sauser, DF … - Diabetes, 2001 - Am Diabetes Assoc Stress conditions and proinflammatory cytokines activate the c-Jun NH 2
-terminal kinase (JNK), a member of the stress-activated group of
mitogen-activated protein kinases (MAPKs). We recently demonstrated that ... Cited by 352 - Related articles - BL Direct - All 4 versions
A Ammendrup, A Maillard, K Nielsen, NA … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc To characterize the differentiation events that selec- tively target
insulin-producing cells to interleukin (IL)- 1 –induced apoptosis, we studied
IL-1 signaling via mitogen-activated protein kinase (MAPK) and stress- ... Cited by 110 - Related articles - BL Direct - All 4 versions
RK Barr, TS Kendrick, MA Bogoyevitch - Journal of Biological Chemistry, 2002 - ASBMB The c-Jun N-terminal kinases (JNKs) are a subfamily of the mitogen-activated
protein kinases (MAPKs). Although progress in evaluating the functions of other
MAPKs has been facilitated by the characterization of specific inhibitors, ... Cited by 122 - Related articles - BL Direct - All 4 versions
- ►jbc.org C Bonny, A Oberson, M Steinmann, DF … - Journal of Biological Chemistry, 2000 - ASBMB IB1/JIP-1 is a scaffold protein that interacts with upstream components of the
c-Jun N-terminal kinase (JNK) signaling pathway. IB1 is expressed at high levels
in pancreatic cells and may therefore exert a tight control on signaling ... Cited by 104 - Related articles - BL Direct - All 5 versions
T Borsello, PGH Clarke, L Hirt, A Vercelli, M … - Nature medicine, 2003 - neuronlab.org Although ischemic stroke is the third most common cause of death in the United
States and Europe, the only currently approved med- ical treatment is
administration of intravenous recombinant tissue plasminogen activator ... Cited by 256 - Related articles - BL Direct - All 22 versions
C Bonny, P Nicod, G Waeber - Journal of Biological Chemistry, 1998 - ASBMB JIP-1 is a cytoplasmic inhibitor of the c-Jun amino-terminal kinase activated
pathway recently cloned from a mouse brain cDNA library. We report herein the
expression cloning of a rat cDNA encoding a JIP-1-related nuclear protein ... Cited by 131 - Related articles - BL Direct - All 4 versions
- ►jneurosci.org J Wang, TR Van De Water, C Bonny, F De … - Journal of Neuroscience, 2003 - Soc Neuroscience We evaluated the otoprotective efficacy of D-JNKI-1, a cell permeable peptide
that blocks the MAPK–JNK signal pathway. The experimental studies included
organ cultures of neonatal mouse cochlea exposed to an ototoxic drug and ... Cited by 122 - Related articles - BL Direct - All 7 versions
G Waeber, J Delplanque, C Bonny, V Mooser, M … - Nature genetics, 2000 - nature.com Type 2 diabetes is a polygenic and genetically heterogenous disease 1 . The age
of onset of the disease is usually late and environmental factors may be
required to induce the complete diabetic phenotype. Susceptibility genes ... Cited by 132 - Related articles - BL Direct - All 3 versions
H Kaneto, Y Nakatani, T Miyatsuka, D … - Nature medicine, 2004 - nature.com The JNK pathway is known to be activated in several tissues in the diabetic
state, and is possibly involved in the development of insulin resistance and
suppression of insulin biosynthesis. Here we show a potential new therapy ... Cited by 166 - Related articles - BL Direct - All 4 versions
M Dickens, JS Rogers, J Cavanagh, A Raitano … - Science, 1997 - sciencemag.org American Association for the Advancement of Science, 1200 New York Avenue NW,
Washington, DC 20005. (print ISSN 0036-8075; online ISSN 1095-9203) is published
weekly, except the last week in December, by the Science Cited by 538 - Related articles - BL Direct - All 9 versions
