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Scholar Results 1 - 10 of about 101 related to Moore: Noninvasive in vivo measurement of β-cell mass in mouse model of diabetes. (0.11 sec) 

Noninvasive in vivo measurement of β-cell mass in mouse model of diabetes

- diabetesjournals.org
A Moore, S Bonner-Weir, R Weissleder - Diabetes, 2001 - Am Diabetes Assoc
Pancreatic β-cell mass (BCM) is a major determinant of the quantity of insulin
that can be secreted. BCM is markedly reduced in type 1 diabetes because of
selective autoimmune destruction of β-cells. Accurate assessment of BCM in ...
Cited by 55 - Related articles - BL Direct - All 4 versions

Systematic screening of potential β-cell imaging agents


IR Sweet, DL Cook, Å Lernmark, CJ … - Biochemical and Biophysical Research …, 2004 - Elsevier
The β-cell loss seen in diabetes mellitus could be monitored clinically by
positron emission tomography (PET) if imaging agents were sufficiently specific
for β-cells to overcome the high ratio of non-β-cell to β-cell tissue in ...
Cited by 32 - Related articles - All 4 versions

Pancreatic fate of a 125 I-labelled mouse monoclonal antibody directed against pancreatic B- …


L Ladri re, F Malaisse-Lagae, R Alejandro, … - Cell Biochemistry and Function, 2001 - 万方数据资源系统
The possible use of a mouse monoclonal antibody directed against rat pancreatic
B-cell surface ganglioside(s) and labelled with radioactive iodine for selective
imaging of the endocrine pancreas by a non-invasive procedure was ...
Cited by 13 - Related articles - BL Direct - All 2 versions

Correlations of in vivo beta-cell function tests with beta-cell mass and pancreatic insulin …


DK McCulloch, DJ Koerker, SE Kahn, S … - Diabetes, 1991 - Am Diabetes Assoc
Cited by 58 - Related articles - All 5 versions

Synthesis and evaluation of fluorine-18 labeled glyburide analogs as β-cell imaging agents


A Schmitz, CY Shiue, Q Feng, GG Shiue, S … - Nuclear medicine and biology, 2004 - Elsevier
Glyburide is a prescribed hypoglycemic drug for the treatment of type 2 diabetic
patients. We have synthesized two of its analogs, namely N-{4-[β-(2-(2′-
fluoroethoxy)-5-chlorobenzenecarboxamido)ethyl]benzenesulfonyl}-N′- ...
Cited by 18 - Related articles - All 5 versions

Uptake of tritiated glibenclamide by endocrine and exocrine pancreas


L Ladriere, F Malaisse-Lagae, WJ Malaisse - Endocrine, 2000 - Springer
Endocrine, vol. 12, no. 3, 329–332, June 2000 0969–711X/00/12:329–332/
$11.00 © 2000 by Humana Press Inc. ... All rights of any nature whatsoever
reserved. ... Tritiated glibenclamide binds to specific receptors and is ...
Cited by 13 - Related articles - BL Direct - All 7 versions

Longitudinal noninvasive PET-based β cell mass estimates in a spontaneous diabetes rat …

- nih.gov
F Souza, N Simpson, A Raffo, C Saxena, A … - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig
1 Department of Medicine and 2 Department of Radiology, Columbia University
Medical Center, New York, New York, USA. 3 Institute of Genetics and Biophysics
“Adriano Buzzati-Traverso,” Consiglio Nazionale delle Ricerche, Naples, ...
Cited by 45 - Related articles - BL Direct - All 9 versions

On the track to the beta-cell


WJ Malaisse - Diabetologia, 2001 - Springer
In his famous article published in the Lancet in 1969 and entitled ªWhy are the
islets of Langerhansº, John Henderson wrote:ªA hundred years ago Paul
Langerhans described, in the most modest way, some pale patches of cells ...
Cited by 17 - Related articles - BL Direct - All 4 versions

In vitro and in vivo evaluation of novel glibenclamide derivatives as imaging agents for the …


S Schneider, PJ Feilen, M Schreckenberger, … - Experimental and clinical endocrinology & diabetes: …, 2005 - ncbi.nlm.nih.gov
Pancreatic islet cell mass (PICM) is a major determinant of the insulin
secretory capacity in humans. Currently, the only method for accurate assessment
of the PICM is an autopsy study. Thus, development of a technique allowing ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Magnetic resonance imaging of pancreatic islets in tolerance and rejection


J Kriz, D Jirák, P Girman, Z Berková, K … - Transplantation, 2005 - journals.lww.com
Transplantation. Wolters Kluwer Health | Lippincott Williams & Wilkins. All Issues. ...
Cited by 38 - Related articles - BL Direct - All 4 versions


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