H Hua, HJ Goldberg, IG Fantus, CI Whiteside - Diabetes, 2001 - Am Diabetes Assoc High glucose (HG) stimulates glomerular mesangial cell (MC) expression of
extracellular matrix, a process involving protein kinase C (PKC) isozymes and
enhanced signaling by autocrine peptides such as endothelin-1 (ET-1). The ... Cited by 32 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org J KAPOR-DREZGIC, X ZHOU, T BABAZONO, … - Journal of the American Society of Nephrology, 1999 - Am Soc Nephrol Abstract. In diabetes mellitus, enhanced activity of mesangial cell protein
kinase C (PKC) may contribute to nephropathy. The purpose of this study was to
determine whether high glucose alters mesangial cell ... Cited by 66 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org [PDF] C Whiteside, S Munk, X Zhou, T Miralem, DM … - Journal of the American Society of Nephrology, 1998 - Am Soc Nephrol Page 1. Chelation of Intracellular Calcium Prevents Mesangial Cell Proliferative
Responsiveness CATHARINE WHITESIDE,* SNEZANA MUNK,* XIAOPENG ZHOU,* ... Cited by 21 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org LK NUTT, RG O'NEIL - Journal of the American Society of Nephrology, 2000 - Am Soc Nephrol Abstract. Early diabetic nephropathy exhibits renal glomerular hyperfiltration
and an increase in renal plasma flow. The hyperfiltration is a dysfunctional
state that may arise from a hyperglycemic-induced hypocontractility of ... Cited by 22 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org [PDF] T Babazono, J Kapor-Drezgic, JA Dlugosz, C … - Diabetes, 1998 - Am Diabetes Assoc Protein kinase C (PKC) is implicated in the pathogen- esis of diabetic
nephropathy. This study was designed to identify the expression of
diacylglycerol (DAG)-sensi- tive PKC- , - II, - , and - isoforms in normal ... Cited by 77 - Related articles - BL Direct - All 4 versions
H Hua, S Munk, H Goldberg, IG Fantus, CI … - Journal of Biological Chemistry, 2003 - ASBMB High glucose (HG) is the underlying factor contributing to long term
complications of diabetes mellitus. The molecular mechanisms transforming the
glomerular mesangial cell phenotype to cause nephropathy including ... Cited by 24 - Related articles - BL Direct - All 2 versions
J Kwan, H Wang, S Munk, L Xia, HJ Goldberg, … - Kidney international, 2005 - nature.com We postulated that in mesangial cells exposed to high glucose, protein kinase C-
(PKC- ) is necessary for the generation of reactive oxygen species (ROS) by
nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and that the ... Cited by 25 - Related articles - BL Direct - All 4 versions
EA Glogowski, E Tsiani, X Zhou, IG Fantus, C … - Kidney international, 1999 - nature.com Rat mesangial cells in primary culture were growth arrested for 48 hours in
glucose 5.6 mM (NG) or 30 mM (HG). PKC- , PKC- , and PKC- translocation from the
cytosol-to-membrane and cytosol-to-particulate (cytoskeleton, nucleus) ... Cited by 42 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org G Dorsam, MM Taher, KC Valerie, NB … - Journal of Pharmacology and Experimental …, 2000 - ASPET Inflammatory cytokines, interleukin 1 and tumor necrosis factor- , potently
stimulate rat mesangial cells to express and secrete group IIA phospholipase A 2
(PLA 2 ). Cytokine-induced up-regulation of PLA 2 has been blocked by ... Cited by 18 - Related articles - BL Direct - All 2 versions
- ►physiology.org [PDF] F Amiri, R Garcia - American Journal of Physiology- Renal Physiology, 1999 - Am Physiological Soc 276:691-699, 1999. Am J Physiol Renal Physiol Farhad Amiri and Raul Garcia ...
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