- ►diabetesjournals.org JE DeHaven, KA Robinson, BA Nelson, MG … - Diabetes, 2001 - Am Diabetes Assoc Glutamine:fructose-6-phosphate amidotransferase(GFAT) is the rate-limiting
enzyme of the hexosamine synthesis pathway. Products of this pathway have been
implicated in insulin resistance and glucose toxicity. GFAT1 is ubiquitous, ... Cited by 13 - Related articles - BL Direct - All 4 versions
M Niimi, T Ogawara, T Yamashita, Y Yamamoto … - Journal of Human Genetics, 2001 - Springer M. Niimi · T. Ogawara · T. Ban · H. Tamanoi · K. Ozaki · T. Fujiwara · E.
Takahashi · H. Kyushiki · A. Tanigami (*) Otsuka GEN Research Institute,
Otsuka Pharmaceutical Co., Ltd., 463-10 Kagasuno, Kawauchi-cho, Tokushima ... Cited by 7 - Related articles - BL Direct - All 4 versions
K Yamazaki, Y Mizui, T Oki, M Okada, I … - Gene, 2000 - Elsevier Glutamine:fructose-6-phosphate amidotransferase (GFAT) is the first and
rate-limiting enzyme of the hexosamine biosynthesis pathway, which plays an
important role in glucose toxicity and cellular insulin resistance. Thus, ... Cited by 6 - Related articles - All 3 versions
T Oki, K Yamazaki, J Kuromitsu, M Okada, I … - Genomics, 1999 - Elsevier We subcloned human and mouse full-length cDNAs of a novel subtype of
glutamine:fructose-6-phosphate amidotransferase (GFAT), which was designated
GFAT2 (the previously reported GFAT was named GFAT1). Both the human and ... Cited by 30 - Related articles - BL Direct - All 5 versions
JE DeHaven, KA Robinson, BA Nelson, MG … - DIABETES, 2001 - Am Diabetes Assoc Glutamine:fructose-6-phosphate amidotransferase (GFAT) is the rate-limiting
enzyme of the hexosamine synthesis pathway. Products of this pathway have been
implicated in insulin resistance and glucose toxicity. GFAT1 is ubiquitous, ... Related articles
TE Whitmore, SL Mudri, GL McKnight - Genomics, 1995 - Elsevier 422 Physical Mapping of the Human Glutamine:Fructose6Phosphate Amidotransferase
Gene (GFPT) to Chromosome 2p13 TE Whitmore,' SL Mudri, and GL McKnight
ZymoGenetics, Inc., 4225 Roosevelt Way North East, Seattle, Washington ... Cited by 10 - Related articles - BL Direct - All 4 versions
J Zhou, JL Neidigh, R Espinosa, MM LeBeau, … - Human genetics, 1995 - Springer Abstract It has been previously shown that some toxic effects of high
concentrations of glucose are mediated by the hexosamine biosynthesis pathway
and its rate-limiting enzyme glutamine:fructose-6-phosphate ... Cited by 16 - Related articles - BL Direct - All 3 versions
S Milewski, M Hoffmann, R Andruszkiewicz, E … - Bioorganic Chemistry, 1997 - Elsevier Several structural analogs of putative tetrahedral intermediates of the reaction
catalyzed by the glutamine amide transfer domain ofCandida albicansglucosamine
6-phosphate synthase have been designed and synthesized. Esters and amides ... Cited by 5 - Related articles - BL Direct - All 3 versions
A Tourian, M Callahan, W Hung - Neurochemical research, 1983 - Springer L-Glutamine t~-Fructose-6-P aminotransferase regulates hexosamine synthesis. An
affinity purified human fibroblast aminotransferase and specific radioisotope
as- says developed by us were used to show an independent inhibition of the ... Cited by 6 - Related articles - All 3 versions
- ►tokushima-u.ac.jp [PDF] K Kunika, T Tanahashi, E Kudo, N Mizusawa, … - Journal of Human Genetics, 2006 - Springer Abstract Glutamine: fructose-6-phosphate amido- transferase 1 (GFPT1) acts as a
rate-limiting enzyme in the hexosamine biosynthetic pathway, which is an
alternative branch of glucose metabolism. To evaluate GFPT1 as a ... Cited by 2 - Related articles - BL Direct - All 8 versions
