J Kamegai, H Tamura, T Shimizu, S Ishii, H Sugihara, I … - Diabetes, 2001 - Am Diabetes Assoc Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHS-R), was
originally purified from the rat stomach. Like the synthetic growth hormone secretagogues
(GHSs), ghrelin specifically releases growth hormone (GH) after intravenous ... Cited by 260 - Related articles - BL Direct - All 4 versions
M Shintani, Y Ogawa, K Ebihara, M Aizawa-Abe, F … - Diabetes, 2001 - Am Diabetes Assoc Ghrelin, an endogenous ligand for growth hormone secretagogue (GHS) receptor originally isolated
from the stomach, occurs in the hypothalamic arcuate nucleus and may play a role in energy
homeostasis. Synthetic GHSs have activated the hypothalamic arcuate neurons ... Cited by 495 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org AM Wren, CJ Small, CR Abbott, WS Dhillo, LJ Seal, MA … - Diabetes, 2001 - Am Diabetes Assoc Ghrelin, a circulating growth hormone–releasing peptide derived from the stomach, stimulates
food intake. The lowest systemically effective orexigenic dose of ghrelin was investigated and
the resulting plasma ghrelin concentration was compared with that during fasting. The ... Cited by 520 - Related articles - BL Direct - All 12 versions
MG Willesen, P Kristensen, J Rømer - Neuroendocrinology, 2000 - content.karger.com Growth hormone secretagogues (GHS) are small, synthetic compounds which have the potential
of releasing growth hormone (GH) from the pituitary. The mechanism of action of GHS has not
been fully elucidated. A specific GHS receptor (GHS-R) is expressed in the pituitary gland ... Cited by 225 - Related articles - BL Direct - All 5 versions
- ►endojournals.org CB Lawrence, AC Snape, FMH Baudoin, SM Luckman - Endocrinology, 2002 - Endocrine Soc Ghrelin was recently identified as the endogenous ligand for the GH secretagogue (GHS)
receptor. Like the synthetic GHSs [eg GH-releasing peptide-6 (GHRP-6)], ghrelin stimulates feeding
and increases body weight in rats. The aim of this study was to identify brain regions that ... Cited by 216 - Related articles - BL Direct - All 4 versions
L Wang, DH Saint-Pierre, Y Taché - Neuroscience letters, 2002 - Elsevier Ghrelin, a peptide isolated from the rat stomach, is the endogenous ligand of the growth
hormone-secretagogue receptor and also known to have orexigenic effect. We examined the
influence of intraperitoneal (ip) injection of ghrelin on food intake and brain neuronal ... Cited by 151 - Related articles - All 4 versions
- ►cell.com MA Cowley, RG Smith, S Diano, M Tschöp, N Pronchuk … - Neuron, 2003 - Elsevier The gastrointestinal peptide hormone ghrelin stimulates appetite in rodents and humans via
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized group
of neurons adjacent to the third ventricle between the dorsal, ventral, paraventricular, and ... Cited by 513 - Related articles - All 13 versions
- ►endojournals.org K Toshinai, Y Date, N Murakami, M Shimada, MS … - Endocrinology, 2003 - Endocrine Soc The hypothalamus regulates energy intake by integrating the degree of starvation or satiation
with the status of the environment through a variety of neuronal and blood-derived signals.
Ghrelin, a peptide produced in the stomach and hypothalamus, stimulates feeding and ... Cited by 191 - Related articles - BL Direct - All 3 versions
- ►endojournals.org TL Horvath, S Diano, P Sotonyi, M Heiman, M Tschop - Endocrinology, 2001 - Endocrine Soc The recently discovered hormone, ghrelin, has been recognized as an important regulator of
GH secretion and energy homeostasis. Orexigenic and adipogenic ghrelin is produced by the
stomach, intestine, placenta, pituitary, and possibly in the hypothalamus. The ... Cited by 369 - Related articles - BL Direct - All 3 versions
