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Scholar Results 1 - 10 of about 101 related to Wren: Ghrelin causes hyperphagia and obesity in rats. (0.10 sec) 

Ghrelin causes hyperphagia and obesity in rats

- diabetesjournals.org
AM Wren, CJ Small, CR Abbott, WS Dhillo, LJ … - Diabetes, 2001 - Am Diabetes Assoc
Ghrelin, a circulating growth hormone–releasing peptide derived from the
stomach, stimulates food intake. The lowest systemically effective orexigenic
dose of ghrelin was investigated and the resulting plasma ghrelin ...
Cited by 517 - Related articles - BL Direct - All 12 versions

Ghrelin enhances appetite and increases food intake in humans


AM Wren, LJ Seal, MA Cohen, AE Brynes, GS … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc
Page 1. 0013-7227/01/$03.00/0 The Journal of Clinical Endocrinology & Metabolism
86(12):5992–5995 Printed in USA Copyright © 2001 by The Endocrine Society ...
Cited by 994 - Related articles - All 14 versions

Ghrelin induces adiposity in rodents


M Tschöp, DL Smiley, ML Heiman - Nature, 2000 - nature.com
The discovery of the peptide hormone ghrelin, an endogenous ligand for the
growth hormone secretagogue (GHS) receptor 1, 2 , yielded the surprising result
3 that the principal site of ghrelin synthesis is the stomach and not the ...
Cited by 1687 - Related articles - BL Direct - All 5 versions

A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans


DE Cummings, JQ Purnell, RS Frayo, K … - Diabetes, 2001 - Am Diabetes Assoc
The recently discovered orexigenic peptide ghrelin is produced primarily by the
stomach and circulates in blood at levels that increase during prolonged fasting
in rats. When administered to rodents at supraphysiological doses, ghrelin ...
Cited by 1115 - Related articles - BL Direct - All 5 versions

The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone …


AM Wren, CJ Small, HL Ward, KG Murphy, CL … - Endocrinology, 2000 - Endocrine Soc
Ghrelin, a novel 28 amino acid peptide found in hypothalamus and stomach, was
recently identified as the endogenous ligand for the growth hormone secretagogue
receptor (GHS-R). We have now found that both intracerebroventricular (ICV) ...
Cited by 802 - Related articles - BL Direct - All 3 versions

Circulating ghrelin levels are decreased in human obesity


M Tschöp, C Weyer, PA Tataranni, V … - Diabetes, 2001 - Am Diabetes Assoc
Ghrelin is a novel endogenous natural ligand for the growth hormone (GH)
secretagogue receptor that has recently been isolated from the rat stomach.
Ghrelin administration stimulates GH secretion but also causes weight gain ...
Cited by 891 - Related articles - BL Direct - All 5 versions

Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti- …


J Kamegai, H Tamura, T Shimizu, S Ishii, H … - Diabetes, 2001 - Am Diabetes Assoc
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor
(GHS-R), was originally purified from the rat stomach. Like the synthetic growth
hormone secretagogues (GHSs), ghrelin specifically releases growth hormone ...
Cited by 258 - Related articles - BL Direct - All 4 versions

A role for ghrelin in the central regulation of feeding


M Nakazato, N Murakami, Y Date, M Kojima, … - Nature, 2001 - nature.com
Ghrelin is an acylated peptide that stimulates the release of growth hormone
from the pituitary 1 . Ghrelin-producing neurons are located in the
hypothalamus, whereas ghrelin receptors are expressed in various regions of ...
Cited by 1375 - Related articles - BL Direct - All 6 versions

Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin


A Asakawa, A Inui, T Kaga, H Yuzuriha, T … - Gastroenterology, 2001 - Elsevier
Results: Ghrelin exhibited gastroprokinetic activity with structural resemblance
to motilin and potent orexigenic activity through action on the hypothalamic
neuropeptide Y (NPY) and Y 1 receptor, which was lost after vagotomy. ...
Cited by 638 - Related articles - BL Direct - All 4 versions

Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that …


M Shintani, Y Ogawa, K Ebihara, M Aizawa- … - Diabetes, 2001 - Am Diabetes Assoc
Ghrelin, an endogenous ligand for growth hormone secretagogue (GHS) receptor
originally isolated from the stomach, occurs in the hypothalamic arcuate nucleus
and may play a role in energy homeostasis. Synthetic GHSs have activated ...
Cited by 493 - Related articles - BL Direct - All 9 versions


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