- ►diabetesjournals.org SA Schreyer, DE Cummings, GS McKnight, … - Diabetes, 2001 - Am Diabetes Assoc The mechanisms by which obesity contributes to diabetic phenotypes remain
unclear. We evaluated the role of protein kinase A (PKA) signaling events in
mediating diabetes associated with obesity. PKA comprises two regulatory ... Cited by 30 - Related articles - BL Direct - All 5 versions
- ►uio.no [PDF] JV Planas, DE Cummings, RL Idzerda, GS … - Journal of Biological Chemistry, 1999 - ASBMB Targeted disruption of the RIIβ subunit of protein kinase A (PKA) produces lean
mice that resist diet-induced obesity. In this report we examine the effects of
the RIIβ knockout on white adipose tissue physiology. Loss of RIIβ is ... Cited by 38 - Related articles - BL Direct - All 7 versions
- ►endojournals.org KJ Newhall, DE Cummings, MA Nolan, GS … - Molecular Endocrinology, 2005 - Endocrine Soc Disruption of the RIIß regulatory subunit of protein kinase A (PKA) results in
mice with a lean phenotype, nocturnal hyperactivity, and increased resting
metabolic rate. In this report, we have examined whether deletion of RIIß ... Cited by 12 - Related articles - All 6 versions
- ►endojournals.org MA Nolan, MA Sikorski, GS McKnight - Molecular Endocrinology, 2004 - Endocrine Soc Mice lacking the RIIß regulatory subunit of protein kinase A exhibit a 50%
reduction in white adipose tissue stores compared with wild-type littermates and
are resistant to diet-induced obesity. RIIß –/– mice also have an ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►j-talk.com TA Czyzyk, MA Sikorski, L Yang, GS McKnight - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Agouti lethal yellow (A y ) mice express agouti ectopically because of a genetic
rearrangement at the agouti locus. The agouti peptide is a potent antagonist of
the melanocortin 4 receptor (MC4R) expressed in neurons, and this leads to ... Cited by 6 - Related articles - BL Direct - All 9 versions
[CITATION] A novel mechanism of cAMP signaling through the interaction of the regulatory subunit of …
- ►cjb.net EP Brandon, SF Logue, MR Adams, M Qi, SP … - Journal of Neuroscience, 1998 - neuro.cjb.net Motor behavior is modulated by dopamine-responsive neurons in the striatum,
where dopaminergic signaling uses G-protein-coupled pathways, including those
that result in the activation of cAMP-dependent protein kinase (PKA). The ... Cited by 84 - Related articles - BL Direct - All 9 versions
- ►jbc.org KA Burton, B Treash-Osio, CH Muller, EL … - Journal of Biological Chemistry, 1999 - ASBMB Cyclic AMP stimulates sperm motility in a variety of mammalian species, but the
molecular details of the intracellular signaling pathway responsible for this
effect are unclear. The type II isoform of protein kinase A (PKA) is ... Cited by 55 - Related articles - BL Direct - All 5 versions
- ►pnas.org MR Adams, EP Brandon, EH Chartoff, RL … - Proceedings of the National Academy of Sciences, 1997 - National Acad Sciences The antipsychotic drug, haloperidol, elicits the expression of neurotensin and
c-fos mRNA in the dorsal lateral region of the striatum and produces an acute
cataleptic response in rodents that correlates with the motor side effects ... Cited by 69 - Related articles - BL Direct - All 10 versions
- ►jbc.org PS Amieux, DE Cummings, K Motamed, EP … - Journal of Biological Chemistry, 1997 - ASBMB The cAMP-dependent protein kinase holoenzyme is assembled from regulatory (R)
and catalytic (C) subunits that are expressed in tissue-specific patterns.
Despite the dispersion of the R and C subunit genes to different ... Cited by 141 - Related articles - BL Direct - All 4 versions
