- ►diabetesjournals.org M Coggins, J Lindner, S Rattigan, L Jahn, E … - Diabetes, 2001 - Am Diabetes Assoc Despite intensive study, the relation between insulin's action on blood flow and
glucose metabolism remains unclear. Insulin-induced changes in microvascular
perfusion, independent from effects on total blood flow, could be an ... Cited by 97 - Related articles - BL Direct - All 5 versions
L Zhang, MA Vincent, SM Richards, LH Clerk, S … - Diabetes, 2004 - Am Diabetes Assoc We have reported that insulin exerts two vascular actions in muscle; it both
increases blood flow and recruits capillaries. In parallel
hyperinsulinemic-euglycemic clamp studies, we compared the insulin dose ... Cited by 57 - Related articles - BL Direct - All 5 versions
MA Vincent, LH Clerk, JR Lindner, AL Klibanov … - Diabetes, 2004 - Am Diabetes Assoc Insulin increases glucose disposal into muscle. In addition, in vivo insulin
elicits distinct nitric oxide synthase-dependent vascular responses to increase
total skeletal muscle blood flow and to recruit muscle capillaries (by ... Cited by 101 - Related articles - BL Direct - All 5 versions
LH Clerk, S Rattigan, MG Clark - Diabetes, 2002 - Am Diabetes Assoc Infusion of triglycerides and heparin causes insulin resistance in muscle.
Because the vascular actions of insulin, particularly capillary recruitment, may
contribute to the increase in glucose uptake by skeletal muscle, we ... Cited by 76 - Related articles - BL Direct - All 5 versions
S Rattigan, MG Clark, EJ Barrett - Diabetes, 1997 - Am Diabetes Assoc Insulin-induced increases in blood flow are hypothesized to enhance overall
glucose uptake by skeletal muscle. Whether the insulin-mediated changes in blood
flow are associated with altered blood flow distribution and increased ... Cited by 135 - Related articles - BL Direct - All 4 versions
- ►physiology.org MA Vincent, EJ Barrett, JR Lindner, MG Clark, … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc We examined the effects of inhibiting nitric oxide synthase with N
-nitro-L-arginine-methyl ester (L-NAME) on total hindlimb blood flow, muscle
microvascular recruitment, and hindlimb glucose uptake during euglycemic ... Cited by 89 - Related articles - BL Direct - All 3 versions
MG Wallis, CM Wheatley, S Rattigan, EJ … - Diabetes, 2002 - Am Diabetes Assoc Insulin-mediated hemodynamic effects in muscle were assessed in relation to
insulin resistance in obese and lean Zucker rats. Whole-body glucose infusion
rate (GIR), femoral blood flow (FBF), hindleg glucose extraction (HGE), ... Cited by 59 - Related articles - BL Direct - All 4 versions
MA Vincent, D Dawson, ADH Clark, JR Lindner, … - Diabetes, 2002 - Am Diabetes Assoc Supraphysiological doses of insulin enhance total limb blood flow and recruit
capillaries in skeletal muscle. Whether these processes change in response to
physiological hyperinsulinemia is uncertain. To examine this, we infused ... Cited by 78 - Related articles - BL Direct - All 5 versions
LH Clerk, MA Vincent, LA Jahn, Z Liu, JR … - Diabetes, 2006 - Am Diabetes Assoc We have previously shown that skeletal muscle capillaries are rapidly recruited
by physiological doses of insulin in both humans and animals. This facilitates
glucose and insulin delivery to muscle, thus augmenting glucose uptake. In ... Cited by 56 - Related articles - BL Direct - All 5 versions
JM Youd, S Rattigan, MG Clark - Diabetes, 2000 - Am Diabetes Assoc The vascular actions of insulin may contribute to the increase in glucose uptake
by skeletal muscle. We have recently shown that when capillary recruitment by
insulin is blocked in vivo, an acute state of insulin resistance is ... Cited by 95 - Related articles - BL Direct - All 4 versions
